Overexpression of endophilin A1 exacerbates synaptic alterations in a mouse model of Alzheimer’s disease

Overexpression of endophilin A1 exacerbates synaptic alterations in a mouse model of Alzheimer’s disease

Endophilin A1 protein is known to be elevated in Alzheimer’s disease (AD). Here the authors show that endophilin A1 overexpression exacerbates synaptic deficits in a mouse model of AD.

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Autores principales: Qing Yu, Yongfu Wang, Fang Du, Shijun Yan, Gang Hu, Nicola Origlia, Grazia Rutigliano, Qinru Sun, Haiyang Yu, James Ainge, Shi Fang Yan, Frank Gunn-Moore, Shirley ShiDu Yan
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2018
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Acceso en línea:https://doaj.org/article/2b7d14570b704403a8911fa6f33a7152
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spelling oai:doaj.org-article:2b7d14570b704403a8911fa6f33a71522021-12-02T14:39:25ZOverexpression of endophilin A1 exacerbates synaptic alterations in a mouse model of Alzheimer’s disease10.1038/s41467-018-04389-02041-1723https://doaj.org/article/2b7d14570b704403a8911fa6f33a71522018-07-01T00:00:00Zhttps://doi.org/10.1038/s41467-018-04389-0https://doaj.org/toc/2041-1723Endophilin A1 protein is known to be elevated in Alzheimer’s disease (AD). Here the authors show that endophilin A1 overexpression exacerbates synaptic deficits in a mouse model of AD.Qing YuYongfu WangFang DuShijun YanGang HuNicola OrigliaGrazia RutiglianoQinru SunHaiyang YuJames AingeShi Fang YanFrank Gunn-MooreShirley ShiDu YanNature PortfolioarticleScienceQENNature Communications, Vol 9, Iss 1, Pp 1-14 (2018)
institution DOAJ
collection DOAJ
language EN
topic Science
Q
spellingShingle Science
Q
Qing Yu
Yongfu Wang
Fang Du
Shijun Yan
Gang Hu
Nicola Origlia
Grazia Rutigliano
Qinru Sun
Haiyang Yu
James Ainge
Shi Fang Yan
Frank Gunn-Moore
Shirley ShiDu Yan
Overexpression of endophilin A1 exacerbates synaptic alterations in a mouse model of Alzheimer’s disease
description Endophilin A1 protein is known to be elevated in Alzheimer’s disease (AD). Here the authors show that endophilin A1 overexpression exacerbates synaptic deficits in a mouse model of AD.
format article
author Qing Yu
Yongfu Wang
Fang Du
Shijun Yan
Gang Hu
Nicola Origlia
Grazia Rutigliano
Qinru Sun
Haiyang Yu
James Ainge
Shi Fang Yan
Frank Gunn-Moore
Shirley ShiDu Yan
author_facet Qing Yu
Yongfu Wang
Fang Du
Shijun Yan
Gang Hu
Nicola Origlia
Grazia Rutigliano
Qinru Sun
Haiyang Yu
James Ainge
Shi Fang Yan
Frank Gunn-Moore
Shirley ShiDu Yan
author_sort Qing Yu
title Overexpression of endophilin A1 exacerbates synaptic alterations in a mouse model of Alzheimer’s disease
title_short Overexpression of endophilin A1 exacerbates synaptic alterations in a mouse model of Alzheimer’s disease
title_full Overexpression of endophilin A1 exacerbates synaptic alterations in a mouse model of Alzheimer’s disease
title_fullStr Overexpression of endophilin A1 exacerbates synaptic alterations in a mouse model of Alzheimer’s disease
title_full_unstemmed Overexpression of endophilin A1 exacerbates synaptic alterations in a mouse model of Alzheimer’s disease
title_sort overexpression of endophilin a1 exacerbates synaptic alterations in a mouse model of alzheimer’s disease
publisher Nature Portfolio
publishDate 2018
url https://doaj.org/article/2b7d14570b704403a8911fa6f33a7152
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