Tenomodulin promotes human adipocyte differentiation and beneficial visceral adipose tissue expansion
Expansion of visceral adipose tissue is usually associated with insulin resistance and metabolic disease. Here, the authors show that the membrane protein TNMD is upregulated in visceral fat of insulin resistant obese individuals and promotes healthy adipose tissue expansion through increasing adipo...
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Nature Portfolio
2016
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oai:doaj.org-article:2b8301dcb67b41eabe00ec0fa2a01c482021-12-02T15:34:30ZTenomodulin promotes human adipocyte differentiation and beneficial visceral adipose tissue expansion10.1038/ncomms106862041-1723https://doaj.org/article/2b8301dcb67b41eabe00ec0fa2a01c482016-02-01T00:00:00Zhttps://doi.org/10.1038/ncomms10686https://doaj.org/toc/2041-1723Expansion of visceral adipose tissue is usually associated with insulin resistance and metabolic disease. Here, the authors show that the membrane protein TNMD is upregulated in visceral fat of insulin resistant obese individuals and promotes healthy adipose tissue expansion through increasing adipogenesis.Ozlem Senol-CosarRachel J. Roth FlachMarina DiStefanoAnil ChawlaSarah NicoloroJuerg StraubhaarOlga T. HardyHye Lim NohJason K. KimMartin WabitschPhilipp E. SchererMichael P. CzechNature PortfolioarticleScienceQENNature Communications, Vol 7, Iss 1, Pp 1-13 (2016) |
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DOAJ |
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EN |
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Science Q |
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Science Q Ozlem Senol-Cosar Rachel J. Roth Flach Marina DiStefano Anil Chawla Sarah Nicoloro Juerg Straubhaar Olga T. Hardy Hye Lim Noh Jason K. Kim Martin Wabitsch Philipp E. Scherer Michael P. Czech Tenomodulin promotes human adipocyte differentiation and beneficial visceral adipose tissue expansion |
description |
Expansion of visceral adipose tissue is usually associated with insulin resistance and metabolic disease. Here, the authors show that the membrane protein TNMD is upregulated in visceral fat of insulin resistant obese individuals and promotes healthy adipose tissue expansion through increasing adipogenesis. |
format |
article |
author |
Ozlem Senol-Cosar Rachel J. Roth Flach Marina DiStefano Anil Chawla Sarah Nicoloro Juerg Straubhaar Olga T. Hardy Hye Lim Noh Jason K. Kim Martin Wabitsch Philipp E. Scherer Michael P. Czech |
author_facet |
Ozlem Senol-Cosar Rachel J. Roth Flach Marina DiStefano Anil Chawla Sarah Nicoloro Juerg Straubhaar Olga T. Hardy Hye Lim Noh Jason K. Kim Martin Wabitsch Philipp E. Scherer Michael P. Czech |
author_sort |
Ozlem Senol-Cosar |
title |
Tenomodulin promotes human adipocyte differentiation and beneficial visceral adipose tissue expansion |
title_short |
Tenomodulin promotes human adipocyte differentiation and beneficial visceral adipose tissue expansion |
title_full |
Tenomodulin promotes human adipocyte differentiation and beneficial visceral adipose tissue expansion |
title_fullStr |
Tenomodulin promotes human adipocyte differentiation and beneficial visceral adipose tissue expansion |
title_full_unstemmed |
Tenomodulin promotes human adipocyte differentiation and beneficial visceral adipose tissue expansion |
title_sort |
tenomodulin promotes human adipocyte differentiation and beneficial visceral adipose tissue expansion |
publisher |
Nature Portfolio |
publishDate |
2016 |
url |
https://doaj.org/article/2b8301dcb67b41eabe00ec0fa2a01c48 |
work_keys_str_mv |
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