Tenomodulin promotes human adipocyte differentiation and beneficial visceral adipose tissue expansion

Expansion of visceral adipose tissue is usually associated with insulin resistance and metabolic disease. Here, the authors show that the membrane protein TNMD is upregulated in visceral fat of insulin resistant obese individuals and promotes healthy adipose tissue expansion through increasing adipo...

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Autores principales: Ozlem Senol-Cosar, Rachel J. Roth Flach, Marina DiStefano, Anil Chawla, Sarah Nicoloro, Juerg Straubhaar, Olga T. Hardy, Hye Lim Noh, Jason K. Kim, Martin Wabitsch, Philipp E. Scherer, Michael P. Czech
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Lenguaje:EN
Publicado: Nature Portfolio 2016
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Acceso en línea:https://doaj.org/article/2b8301dcb67b41eabe00ec0fa2a01c48
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spelling oai:doaj.org-article:2b8301dcb67b41eabe00ec0fa2a01c482021-12-02T15:34:30ZTenomodulin promotes human adipocyte differentiation and beneficial visceral adipose tissue expansion10.1038/ncomms106862041-1723https://doaj.org/article/2b8301dcb67b41eabe00ec0fa2a01c482016-02-01T00:00:00Zhttps://doi.org/10.1038/ncomms10686https://doaj.org/toc/2041-1723Expansion of visceral adipose tissue is usually associated with insulin resistance and metabolic disease. Here, the authors show that the membrane protein TNMD is upregulated in visceral fat of insulin resistant obese individuals and promotes healthy adipose tissue expansion through increasing adipogenesis.Ozlem Senol-CosarRachel J. Roth FlachMarina DiStefanoAnil ChawlaSarah NicoloroJuerg StraubhaarOlga T. HardyHye Lim NohJason K. KimMartin WabitschPhilipp E. SchererMichael P. CzechNature PortfolioarticleScienceQENNature Communications, Vol 7, Iss 1, Pp 1-13 (2016)
institution DOAJ
collection DOAJ
language EN
topic Science
Q
spellingShingle Science
Q
Ozlem Senol-Cosar
Rachel J. Roth Flach
Marina DiStefano
Anil Chawla
Sarah Nicoloro
Juerg Straubhaar
Olga T. Hardy
Hye Lim Noh
Jason K. Kim
Martin Wabitsch
Philipp E. Scherer
Michael P. Czech
Tenomodulin promotes human adipocyte differentiation and beneficial visceral adipose tissue expansion
description Expansion of visceral adipose tissue is usually associated with insulin resistance and metabolic disease. Here, the authors show that the membrane protein TNMD is upregulated in visceral fat of insulin resistant obese individuals and promotes healthy adipose tissue expansion through increasing adipogenesis.
format article
author Ozlem Senol-Cosar
Rachel J. Roth Flach
Marina DiStefano
Anil Chawla
Sarah Nicoloro
Juerg Straubhaar
Olga T. Hardy
Hye Lim Noh
Jason K. Kim
Martin Wabitsch
Philipp E. Scherer
Michael P. Czech
author_facet Ozlem Senol-Cosar
Rachel J. Roth Flach
Marina DiStefano
Anil Chawla
Sarah Nicoloro
Juerg Straubhaar
Olga T. Hardy
Hye Lim Noh
Jason K. Kim
Martin Wabitsch
Philipp E. Scherer
Michael P. Czech
author_sort Ozlem Senol-Cosar
title Tenomodulin promotes human adipocyte differentiation and beneficial visceral adipose tissue expansion
title_short Tenomodulin promotes human adipocyte differentiation and beneficial visceral adipose tissue expansion
title_full Tenomodulin promotes human adipocyte differentiation and beneficial visceral adipose tissue expansion
title_fullStr Tenomodulin promotes human adipocyte differentiation and beneficial visceral adipose tissue expansion
title_full_unstemmed Tenomodulin promotes human adipocyte differentiation and beneficial visceral adipose tissue expansion
title_sort tenomodulin promotes human adipocyte differentiation and beneficial visceral adipose tissue expansion
publisher Nature Portfolio
publishDate 2016
url https://doaj.org/article/2b8301dcb67b41eabe00ec0fa2a01c48
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