An integrative analysis of the age-associated multi-omic landscape across cancers

Our understanding of the age-related molecular alterations in cancer is still limited. Here, the authors perform a pan-cancer analysis of age-associated genomic, transcriptomic, and epigenetic alterations, linking age-related gene expression changes to age-related DNA methylation alterations

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Autores principales:	Kasit Chatsirisupachai, Tom Lesluyes, Luminita Paraoan, Peter Van Loo, João Pedro de Magalhães
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2021
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/2b870963a0af42f4b41c71233cf59c2e
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spelling	oai:doaj.org-article:2b870963a0af42f4b41c71233cf59c2e2021-12-02T16:45:05ZAn integrative analysis of the age-associated multi-omic landscape across cancers10.1038/s41467-021-22560-y2041-1723https://doaj.org/article/2b870963a0af42f4b41c71233cf59c2e2021-04-01T00:00:00Zhttps://doi.org/10.1038/s41467-021-22560-yhttps://doaj.org/toc/2041-1723Our understanding of the age-related molecular alterations in cancer is still limited. Here, the authors perform a pan-cancer analysis of age-associated genomic, transcriptomic, and epigenetic alterations, linking age-related gene expression changes to age-related DNA methylation alterationsKasit ChatsirisupachaiTom LesluyesLuminita ParaoanPeter Van LooJoão Pedro de MagalhãesNature PortfolioarticleScienceQENNature Communications, Vol 12, Iss 1, Pp 1-17 (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Kasit Chatsirisupachai Tom Lesluyes Luminita Paraoan Peter Van Loo João Pedro de Magalhães An integrative analysis of the age-associated multi-omic landscape across cancers
description	Our understanding of the age-related molecular alterations in cancer is still limited. Here, the authors perform a pan-cancer analysis of age-associated genomic, transcriptomic, and epigenetic alterations, linking age-related gene expression changes to age-related DNA methylation alterations
format	article
author	Kasit Chatsirisupachai Tom Lesluyes Luminita Paraoan Peter Van Loo João Pedro de Magalhães
author_facet	Kasit Chatsirisupachai Tom Lesluyes Luminita Paraoan Peter Van Loo João Pedro de Magalhães
author_sort	Kasit Chatsirisupachai
title	An integrative analysis of the age-associated multi-omic landscape across cancers
title_short	An integrative analysis of the age-associated multi-omic landscape across cancers
title_full	An integrative analysis of the age-associated multi-omic landscape across cancers
title_fullStr	An integrative analysis of the age-associated multi-omic landscape across cancers
title_full_unstemmed	An integrative analysis of the age-associated multi-omic landscape across cancers
title_sort	integrative analysis of the age-associated multi-omic landscape across cancers
publisher	Nature Portfolio
publishDate	2021
url	https://doaj.org/article/2b870963a0af42f4b41c71233cf59c2e
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An integrative analysis of the age-associated multi-omic landscape across cancers

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