Hypoxia-induced TET1 facilitates trophoblast cell migration and invasion through HIF1α signaling pathway

Hypoxia-induced TET1 facilitates trophoblast cell migration and invasion through HIF1α signaling pathway

Abstract Low oxygen is a typical extrinsic factor for the regulation of trophoblast biological function, including cell migration, invasion and proliferation. Ten-eleven translocation methylcytosine dioxygenase 1 (TET1), an enzyme converting 5-methylcytosine (5-mC) to 5-hydroxymethylcytosine (5-hmC)...

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Autores principales: Jingping Zhu, Kai Wang, Ting Li, Jiayu Chen, Dandan Xie, Xinwen Chang, Julei Yao, Jinting Wu, Qian Zhou, Yuanhui Jia, Tao Duan
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2017
Materias:
Medicine
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Science
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Acceso en línea:https://doaj.org/article/2b9ca6fbdfb8432b9dd8b3d62603757c
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