Evolution of heterogeneity (I2) estimates and their 95% confidence intervals in large meta-analyses.

<h4>Background</h4>Assessment of heterogeneity is essential in systematic reviews and meta-analyses of clinical trials. The most commonly used heterogeneity measure, I(2), provides an estimate of the proportion of variability in a meta-analysis that is explained by differences between th...

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Main Authors: Kristian Thorlund, Georgina Imberger, Bradley C Johnston, Michael Walsh, Tahany Awad, Lehana Thabane, Christian Gluud, P J Devereaux, Jørn Wetterslev
Format: article
Language:EN
Published: Public Library of Science (PLoS) 2012
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R
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Online Access:https://doaj.org/article/2ba7b850c09a4314b90e67308aea09d3
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