Cripto is essential to capture mouse epiblast stem cell and human embryonic stem cell pluripotency
Stem cell plasticity is crucial for early embryo development and the differentiation of stem cells. Here, the authors show that the extracellular protein Cripto sustains mouse ESC self-renewal and maintains mouse EpiSC as well as human ESC pluripotency and controls the metabolic reprogramming in ESC...
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Nature Portfolio
2016
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oai:doaj.org-article:2bb01357f66344a6adf138525180fdf02021-12-02T17:32:37ZCripto is essential to capture mouse epiblast stem cell and human embryonic stem cell pluripotency10.1038/ncomms125892041-1723https://doaj.org/article/2bb01357f66344a6adf138525180fdf02016-09-01T00:00:00Zhttps://doi.org/10.1038/ncomms12589https://doaj.org/toc/2041-1723Stem cell plasticity is crucial for early embryo development and the differentiation of stem cells. Here, the authors show that the extracellular protein Cripto sustains mouse ESC self-renewal and maintains mouse EpiSC as well as human ESC pluripotency and controls the metabolic reprogramming in ESCs to EpiSC transition.Alessandro FiorenzanoEmilia PascaleCristina D'AnielloDario AcamporaCecilia BassalertFrancesco RussoGennaro AndolfiMauro BiffoniFederica FrancescangeliAnn ZeunerClaudia AngeliniClaire ChazaudEduardo J. PatriarcaAnnalisa FicoGabriella MinchiottiNature PortfolioarticleScienceQENNature Communications, Vol 7, Iss 1, Pp 1-16 (2016) |
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Science Q |
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Science Q Alessandro Fiorenzano Emilia Pascale Cristina D'Aniello Dario Acampora Cecilia Bassalert Francesco Russo Gennaro Andolfi Mauro Biffoni Federica Francescangeli Ann Zeuner Claudia Angelini Claire Chazaud Eduardo J. Patriarca Annalisa Fico Gabriella Minchiotti Cripto is essential to capture mouse epiblast stem cell and human embryonic stem cell pluripotency |
description |
Stem cell plasticity is crucial for early embryo development and the differentiation of stem cells. Here, the authors show that the extracellular protein Cripto sustains mouse ESC self-renewal and maintains mouse EpiSC as well as human ESC pluripotency and controls the metabolic reprogramming in ESCs to EpiSC transition. |
format |
article |
author |
Alessandro Fiorenzano Emilia Pascale Cristina D'Aniello Dario Acampora Cecilia Bassalert Francesco Russo Gennaro Andolfi Mauro Biffoni Federica Francescangeli Ann Zeuner Claudia Angelini Claire Chazaud Eduardo J. Patriarca Annalisa Fico Gabriella Minchiotti |
author_facet |
Alessandro Fiorenzano Emilia Pascale Cristina D'Aniello Dario Acampora Cecilia Bassalert Francesco Russo Gennaro Andolfi Mauro Biffoni Federica Francescangeli Ann Zeuner Claudia Angelini Claire Chazaud Eduardo J. Patriarca Annalisa Fico Gabriella Minchiotti |
author_sort |
Alessandro Fiorenzano |
title |
Cripto is essential to capture mouse epiblast stem cell and human embryonic stem cell pluripotency |
title_short |
Cripto is essential to capture mouse epiblast stem cell and human embryonic stem cell pluripotency |
title_full |
Cripto is essential to capture mouse epiblast stem cell and human embryonic stem cell pluripotency |
title_fullStr |
Cripto is essential to capture mouse epiblast stem cell and human embryonic stem cell pluripotency |
title_full_unstemmed |
Cripto is essential to capture mouse epiblast stem cell and human embryonic stem cell pluripotency |
title_sort |
cripto is essential to capture mouse epiblast stem cell and human embryonic stem cell pluripotency |
publisher |
Nature Portfolio |
publishDate |
2016 |
url |
https://doaj.org/article/2bb01357f66344a6adf138525180fdf0 |
work_keys_str_mv |
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