Silica/Protein and Silica/Polysaccharide Interactions and Their Contributions to the Functional Properties of Derived Hybrid Wound Dressing Hydrogels

Multifunctional and biocompatible hydrogels are on the focus of wound healing treatments. Protein and polysaccharides silica hybrids are interesting wound dressing alternatives. The objective of this review is to answer questions such as why silica for wound dressings reinforcement? What are the rol...

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Autores principales:	Monica Mesa, Natalia Y. Becerra
Formato:	article
Lenguaje:	EN
Publicado:	Hindawi Limited 2021
Materias:	Biotechnology TP248.13-248.65
Acceso en línea:	https://doaj.org/article/2bb2beae9b2549459abda2488f8aaaa8
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spelling	oai:doaj.org-article:2bb2beae9b2549459abda2488f8aaaa82021-11-15T01:18:55ZSilica/Protein and Silica/Polysaccharide Interactions and Their Contributions to the Functional Properties of Derived Hybrid Wound Dressing Hydrogels1687-879510.1155/2021/6857204https://doaj.org/article/2bb2beae9b2549459abda2488f8aaaa82021-01-01T00:00:00Zhttp://dx.doi.org/10.1155/2021/6857204https://doaj.org/toc/1687-8795Multifunctional and biocompatible hydrogels are on the focus of wound healing treatments. Protein and polysaccharides silica hybrids are interesting wound dressing alternatives. The objective of this review is to answer questions such as why silica for wound dressings reinforcement? What are the roles and contributions of silane precursors and silica on the functional properties of hydrogel wound dressings? The effects of tailoring the porous, morphological, and chemical characteristics of synthetic silicas on the bioactivity of hybrid wound dressings hydrogels are explored in the first part of the review. This is followed by a commented review of the mechanisms of silica/protein and silica/polysaccharide interactions and their impact on the barrier, scaffold, and delivery matrix functions of the derived hydrogels. Such information has important consequences for wound healing and paves the way to multidisciplinary researches on the production, processing, and biomedical application of this kind of hybrid materials.Monica MesaNatalia Y. BecerraHindawi LimitedarticleBiotechnologyTP248.13-248.65ENInternational Journal of Biomaterials, Vol 2021 (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	Biotechnology TP248.13-248.65
spellingShingle	Biotechnology TP248.13-248.65 Monica Mesa Natalia Y. Becerra Silica/Protein and Silica/Polysaccharide Interactions and Their Contributions to the Functional Properties of Derived Hybrid Wound Dressing Hydrogels
description	Multifunctional and biocompatible hydrogels are on the focus of wound healing treatments. Protein and polysaccharides silica hybrids are interesting wound dressing alternatives. The objective of this review is to answer questions such as why silica for wound dressings reinforcement? What are the roles and contributions of silane precursors and silica on the functional properties of hydrogel wound dressings? The effects of tailoring the porous, morphological, and chemical characteristics of synthetic silicas on the bioactivity of hybrid wound dressings hydrogels are explored in the first part of the review. This is followed by a commented review of the mechanisms of silica/protein and silica/polysaccharide interactions and their impact on the barrier, scaffold, and delivery matrix functions of the derived hydrogels. Such information has important consequences for wound healing and paves the way to multidisciplinary researches on the production, processing, and biomedical application of this kind of hybrid materials.
format	article
author	Monica Mesa Natalia Y. Becerra
author_facet	Monica Mesa Natalia Y. Becerra
author_sort	Monica Mesa
title	Silica/Protein and Silica/Polysaccharide Interactions and Their Contributions to the Functional Properties of Derived Hybrid Wound Dressing Hydrogels
title_short	Silica/Protein and Silica/Polysaccharide Interactions and Their Contributions to the Functional Properties of Derived Hybrid Wound Dressing Hydrogels
title_full	Silica/Protein and Silica/Polysaccharide Interactions and Their Contributions to the Functional Properties of Derived Hybrid Wound Dressing Hydrogels
title_fullStr	Silica/Protein and Silica/Polysaccharide Interactions and Their Contributions to the Functional Properties of Derived Hybrid Wound Dressing Hydrogels
title_full_unstemmed	Silica/Protein and Silica/Polysaccharide Interactions and Their Contributions to the Functional Properties of Derived Hybrid Wound Dressing Hydrogels
title_sort	silica/protein and silica/polysaccharide interactions and their contributions to the functional properties of derived hybrid wound dressing hydrogels
publisher	Hindawi Limited
publishDate	2021
url	https://doaj.org/article/2bb2beae9b2549459abda2488f8aaaa8
work_keys_str_mv	AT monicamesa silicaproteinandsilicapolysaccharideinteractionsandtheircontributionstothefunctionalpropertiesofderivedhybridwounddressinghydrogels AT nataliaybecerra silicaproteinandsilicapolysaccharideinteractionsandtheircontributionstothefunctionalpropertiesofderivedhybridwounddressinghydrogels
_version_	1718428971953029120

Silica/Protein and Silica/Polysaccharide Interactions and Their Contributions to the Functional Properties of Derived Hybrid Wound Dressing Hydrogels

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