Noise reduction as an emergent property of single-cell aging

Gene expression is a noisy process, but it is not known how noise in gene expression changes during the aging of single cells. Here the authors show that noise decreases during normal aging, and provide support for aging-associated increases in chromatin state transitions governing noise reduction.

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Detalles Bibliográficos
Autores principales:	Ping Liu, Ruijie Song, Gregory L. Elison, Weilin Peng, Murat Acar
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2017
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/2bb6b626d6f2403eb82c336018dcf06e
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spelling	oai:doaj.org-article:2bb6b626d6f2403eb82c336018dcf06e2021-12-02T15:38:53ZNoise reduction as an emergent property of single-cell aging10.1038/s41467-017-00752-92041-1723https://doaj.org/article/2bb6b626d6f2403eb82c336018dcf06e2017-09-01T00:00:00Zhttps://doi.org/10.1038/s41467-017-00752-9https://doaj.org/toc/2041-1723Gene expression is a noisy process, but it is not known how noise in gene expression changes during the aging of single cells. Here the authors show that noise decreases during normal aging, and provide support for aging-associated increases in chromatin state transitions governing noise reduction.Ping LiuRuijie SongGregory L. ElisonWeilin PengMurat AcarNature PortfolioarticleScienceQENNature Communications, Vol 8, Iss 1, Pp 1-13 (2017)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Ping Liu Ruijie Song Gregory L. Elison Weilin Peng Murat Acar Noise reduction as an emergent property of single-cell aging
description	Gene expression is a noisy process, but it is not known how noise in gene expression changes during the aging of single cells. Here the authors show that noise decreases during normal aging, and provide support for aging-associated increases in chromatin state transitions governing noise reduction.
format	article
author	Ping Liu Ruijie Song Gregory L. Elison Weilin Peng Murat Acar
author_facet	Ping Liu Ruijie Song Gregory L. Elison Weilin Peng Murat Acar
author_sort	Ping Liu
title	Noise reduction as an emergent property of single-cell aging
title_short	Noise reduction as an emergent property of single-cell aging
title_full	Noise reduction as an emergent property of single-cell aging
title_fullStr	Noise reduction as an emergent property of single-cell aging
title_full_unstemmed	Noise reduction as an emergent property of single-cell aging
title_sort	noise reduction as an emergent property of single-cell aging
publisher	Nature Portfolio
publishDate	2017
url	https://doaj.org/article/2bb6b626d6f2403eb82c336018dcf06e
work_keys_str_mv	AT pingliu noisereductionasanemergentpropertyofsinglecellaging AT ruijiesong noisereductionasanemergentpropertyofsinglecellaging AT gregorylelison noisereductionasanemergentpropertyofsinglecellaging AT weilinpeng noisereductionasanemergentpropertyofsinglecellaging AT muratacar noisereductionasanemergentpropertyofsinglecellaging
_version_	1718386040006246400

Noise reduction as an emergent property of single-cell aging

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