Noise reduction as an emergent property of single-cell aging

Gene expression is a noisy process, but it is not known how noise in gene expression changes during the aging of single cells. Here the authors show that noise decreases during normal aging, and provide support for aging-associated increases in chromatin state transitions governing noise reduction.

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Detalles Bibliográficos
Autores principales: Ping Liu, Ruijie Song, Gregory L. Elison, Weilin Peng, Murat Acar
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2017
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Acceso en línea:https://doaj.org/article/2bb6b626d6f2403eb82c336018dcf06e
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