Endothelium-specific depletion of LRP1 improves glucose homeostasis through inducing osteocalcin

The vascular endothelium contributes to metabolic regulation, however, the underlying mechanisms are not fully understood. Here the authors show that endothelial low-density lipoprotein receptor-related protein 1 regulates glucose homeostasis via osteocalcin expression.

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Autores principales:	Hua Mao, Luge Li, Qiying Fan, Aude Angelini, Pradip K. Saha, Cristian Coarfa, Kimal Rajapakshe, Dimuthu Perera, Jizhong Cheng, Huaizhu Wu, Christie M. Ballantyne, Zheng Sun, Liang Xie, Xinchun Pi
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2021
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/2bb6c637cb5f4e2eb55a2f359b4beb74
Etiquetas:	Agregar Etiqueta Sin Etiquetas, Sea el primero en etiquetar este registro!

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spelling	oai:doaj.org-article:2bb6c637cb5f4e2eb55a2f359b4beb742021-12-02T19:12:29ZEndothelium-specific depletion of LRP1 improves glucose homeostasis through inducing osteocalcin10.1038/s41467-021-25673-62041-1723https://doaj.org/article/2bb6c637cb5f4e2eb55a2f359b4beb742021-09-01T00:00:00Zhttps://doi.org/10.1038/s41467-021-25673-6https://doaj.org/toc/2041-1723The vascular endothelium contributes to metabolic regulation, however, the underlying mechanisms are not fully understood. Here the authors show that endothelial low-density lipoprotein receptor-related protein 1 regulates glucose homeostasis via osteocalcin expression.Hua MaoLuge LiQiying FanAude AngeliniPradip K. SahaCristian CoarfaKimal RajapaksheDimuthu PereraJizhong ChengHuaizhu WuChristie M. BallantyneZheng SunLiang XieXinchun PiNature PortfolioarticleScienceQENNature Communications, Vol 12, Iss 1, Pp 1-12 (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Hua Mao Luge Li Qiying Fan Aude Angelini Pradip K. Saha Cristian Coarfa Kimal Rajapakshe Dimuthu Perera Jizhong Cheng Huaizhu Wu Christie M. Ballantyne Zheng Sun Liang Xie Xinchun Pi Endothelium-specific depletion of LRP1 improves glucose homeostasis through inducing osteocalcin
description	The vascular endothelium contributes to metabolic regulation, however, the underlying mechanisms are not fully understood. Here the authors show that endothelial low-density lipoprotein receptor-related protein 1 regulates glucose homeostasis via osteocalcin expression.
format	article
author	Hua Mao Luge Li Qiying Fan Aude Angelini Pradip K. Saha Cristian Coarfa Kimal Rajapakshe Dimuthu Perera Jizhong Cheng Huaizhu Wu Christie M. Ballantyne Zheng Sun Liang Xie Xinchun Pi
author_facet	Hua Mao Luge Li Qiying Fan Aude Angelini Pradip K. Saha Cristian Coarfa Kimal Rajapakshe Dimuthu Perera Jizhong Cheng Huaizhu Wu Christie M. Ballantyne Zheng Sun Liang Xie Xinchun Pi
author_sort	Hua Mao
title	Endothelium-specific depletion of LRP1 improves glucose homeostasis through inducing osteocalcin
title_short	Endothelium-specific depletion of LRP1 improves glucose homeostasis through inducing osteocalcin
title_full	Endothelium-specific depletion of LRP1 improves glucose homeostasis through inducing osteocalcin
title_fullStr	Endothelium-specific depletion of LRP1 improves glucose homeostasis through inducing osteocalcin
title_full_unstemmed	Endothelium-specific depletion of LRP1 improves glucose homeostasis through inducing osteocalcin
title_sort	endothelium-specific depletion of lrp1 improves glucose homeostasis through inducing osteocalcin
publisher	Nature Portfolio
publishDate	2021
url	https://doaj.org/article/2bb6c637cb5f4e2eb55a2f359b4beb74
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Endothelium-specific depletion of LRP1 improves glucose homeostasis through inducing osteocalcin

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