Endothelium-specific depletion of LRP1 improves glucose homeostasis through inducing osteocalcin

Endothelium-specific depletion of LRP1 improves glucose homeostasis through inducing osteocalcin

The vascular endothelium contributes to metabolic regulation, however, the underlying mechanisms are not fully understood. Here the authors show that endothelial low-density lipoprotein receptor-related protein 1 regulates glucose homeostasis via osteocalcin expression.

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Bibliographic Details
Main Authors: Hua Mao, Luge Li, Qiying Fan, Aude Angelini, Pradip K. Saha, Cristian Coarfa, Kimal Rajapakshe, Dimuthu Perera, Jizhong Cheng, Huaizhu Wu, Christie M. Ballantyne, Zheng Sun, Liang Xie, Xinchun Pi
Format: article
Language:EN
Published: Nature Portfolio 2021
Subjects:
Science
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Online Access:https://doaj.org/article/2bb6c637cb5f4e2eb55a2f359b4beb74
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https://doaj.org/article/2bb6c637cb5f4e2eb55a2f359b4beb74

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