A systematic evaluation of single cell RNA-seq analysis pipelines

There has been a rapid rise in single cell RNA-seq methods and associated pipelines. Here the authors use simulated data to systematically evaluate the performance of 3000 possible pipelines to derive recommendations for data processing and analysis of different types of scRNA-seq experiments.

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Auteurs principaux:	Beate Vieth, Swati Parekh, Christoph Ziegenhain, Wolfgang Enard, Ines Hellmann
Format:	article
Langue:	EN
Publié:	Nature Portfolio 2019
Sujets:	Science Q
Accès en ligne:	https://doaj.org/article/2bc3c1c113b84eecbdc9f6b415ed696b
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id	oai:doaj.org-article:2bc3c1c113b84eecbdc9f6b415ed696b
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spelling	oai:doaj.org-article:2bc3c1c113b84eecbdc9f6b415ed696b2021-12-02T16:57:56ZA systematic evaluation of single cell RNA-seq analysis pipelines10.1038/s41467-019-12266-72041-1723https://doaj.org/article/2bc3c1c113b84eecbdc9f6b415ed696b2019-10-01T00:00:00Zhttps://doi.org/10.1038/s41467-019-12266-7https://doaj.org/toc/2041-1723There has been a rapid rise in single cell RNA-seq methods and associated pipelines. Here the authors use simulated data to systematically evaluate the performance of 3000 possible pipelines to derive recommendations for data processing and analysis of different types of scRNA-seq experiments.Beate ViethSwati ParekhChristoph ZiegenhainWolfgang EnardInes HellmannNature PortfolioarticleScienceQENNature Communications, Vol 10, Iss 1, Pp 1-11 (2019)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Beate Vieth Swati Parekh Christoph Ziegenhain Wolfgang Enard Ines Hellmann A systematic evaluation of single cell RNA-seq analysis pipelines
description	There has been a rapid rise in single cell RNA-seq methods and associated pipelines. Here the authors use simulated data to systematically evaluate the performance of 3000 possible pipelines to derive recommendations for data processing and analysis of different types of scRNA-seq experiments.
format	article
author	Beate Vieth Swati Parekh Christoph Ziegenhain Wolfgang Enard Ines Hellmann
author_facet	Beate Vieth Swati Parekh Christoph Ziegenhain Wolfgang Enard Ines Hellmann
author_sort	Beate Vieth
title	A systematic evaluation of single cell RNA-seq analysis pipelines
title_short	A systematic evaluation of single cell RNA-seq analysis pipelines
title_full	A systematic evaluation of single cell RNA-seq analysis pipelines
title_fullStr	A systematic evaluation of single cell RNA-seq analysis pipelines
title_full_unstemmed	A systematic evaluation of single cell RNA-seq analysis pipelines
title_sort	systematic evaluation of single cell rna-seq analysis pipelines
publisher	Nature Portfolio
publishDate	2019
url	https://doaj.org/article/2bc3c1c113b84eecbdc9f6b415ed696b
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A systematic evaluation of single cell RNA-seq analysis pipelines

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