Anti-inflammatory activities of ethnomedicinal plants from Dayak Abai in North Kalimantan, Indonesia

Paramita S, Kosala K, Dzulkifli D, Saputri DI, Wijayanti E. 2017. Anti-inflammatory activities of ethnomedicinal plants from Dayak Abai in North Kalimantan, Indonesia. Biodiversitas 18: 1556-1561. Inflammation is a normal process in the human body as a response to injury from the healing process. Me...

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Autores principales:	SWANDARI PARAMITA, KHEMASILI KOSALA, DZULKIFLI DZULKIFLI, DEBY INDAH SAPUTRI, ENGGAR WIJAYANTI
Formato:	article
Lenguaje:	EN
Publicado:	MBI & UNS Solo 2017
Materias:	anti-inflammatory amomum xanthophlebium clerodendrum buchananii donax canniformis carrageenan-induced rat paw edema Biology (General) QH301-705.5
Acceso en línea:	https://doaj.org/article/2bcb5bffe51049158ace0335c9a3c136
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spelling	oai:doaj.org-article:2bcb5bffe51049158ace0335c9a3c1362021-11-16T14:00:12ZAnti-inflammatory activities of ethnomedicinal plants from Dayak Abai in North Kalimantan, Indonesia1412-033X2085-472210.13057/biodiv/d180433https://doaj.org/article/2bcb5bffe51049158ace0335c9a3c1362017-10-01T00:00:00Zhttps://smujo.id/biodiv/article/view/2110https://doaj.org/toc/1412-033Xhttps://doaj.org/toc/2085-4722Paramita S, Kosala K, Dzulkifli D, Saputri DI, Wijayanti E. 2017. Anti-inflammatory activities of ethnomedicinal plants from Dayak Abai in North Kalimantan, Indonesia. Biodiversitas 18: 1556-1561. Inflammation is a normal process in the human body as a response to injury from the healing process. Meanwhile, chronic inflammation will cause new health problems to patients. Antiinflammatory drugs generally used for those conditions, have several side effects to patients. The objective of this research was to find alternative anti-inflammatory drugs, especially from natural sources. Three medicinal plants recorded from Dayak Abai in North Kalimantan, Indonesia for health problems caused by the inflammation process i.e. Amomum xanthophlebium Baker, Clerodendrum buchananii (Roxb.) Walp., and Donax canniformis (G.Forst.) K.Schum. were used as material in this research. The experimental method using carrageenan-induced rat paw edema was used followed by the resulting measurement using plethysmometer. The results showed that significant differences of AUC (area under the curve) with p = 0.001 (p < 0.05) were achieved between negative control, positive control, and treatment group with plant medicinal extracts. AUC of leaves ethanol extract of C. buchananii showed the strongest antiinflammatory activities. It could be concluded that the medicinal plants recorded from ethnomedicinal data from Dayak Abai in North Kalimantan, have anti-inflammatory activities, with C. buchananii as the most potential ones which could be further developed as a new source of the anti-inflammatory drug.SWANDARI PARAMITAKHEMASILI KOSALADZULKIFLI DZULKIFLIDEBY INDAH SAPUTRIENGGAR WIJAYANTIMBI & UNS Soloarticleanti-inflammatoryamomum xanthophlebiumclerodendrum buchananiidonax canniformiscarrageenan-induced rat paw edemaBiology (General)QH301-705.5ENBiodiversitas, Vol 18, Iss 4, Pp 1556-1561 (2017)
institution	DOAJ
collection	DOAJ
language	EN
topic	anti-inflammatory amomum xanthophlebium clerodendrum buchananii donax canniformis carrageenan-induced rat paw edema Biology (General) QH301-705.5
spellingShingle	anti-inflammatory amomum xanthophlebium clerodendrum buchananii donax canniformis carrageenan-induced rat paw edema Biology (General) QH301-705.5 SWANDARI PARAMITA KHEMASILI KOSALA DZULKIFLI DZULKIFLI DEBY INDAH SAPUTRI ENGGAR WIJAYANTI Anti-inflammatory activities of ethnomedicinal plants from Dayak Abai in North Kalimantan, Indonesia
description	Paramita S, Kosala K, Dzulkifli D, Saputri DI, Wijayanti E. 2017. Anti-inflammatory activities of ethnomedicinal plants from Dayak Abai in North Kalimantan, Indonesia. Biodiversitas 18: 1556-1561. Inflammation is a normal process in the human body as a response to injury from the healing process. Meanwhile, chronic inflammation will cause new health problems to patients. Antiinflammatory drugs generally used for those conditions, have several side effects to patients. The objective of this research was to find alternative anti-inflammatory drugs, especially from natural sources. Three medicinal plants recorded from Dayak Abai in North Kalimantan, Indonesia for health problems caused by the inflammation process i.e. Amomum xanthophlebium Baker, Clerodendrum buchananii (Roxb.) Walp., and Donax canniformis (G.Forst.) K.Schum. were used as material in this research. The experimental method using carrageenan-induced rat paw edema was used followed by the resulting measurement using plethysmometer. The results showed that significant differences of AUC (area under the curve) with p = 0.001 (p < 0.05) were achieved between negative control, positive control, and treatment group with plant medicinal extracts. AUC of leaves ethanol extract of C. buchananii showed the strongest antiinflammatory activities. It could be concluded that the medicinal plants recorded from ethnomedicinal data from Dayak Abai in North Kalimantan, have anti-inflammatory activities, with C. buchananii as the most potential ones which could be further developed as a new source of the anti-inflammatory drug.
format	article
author	SWANDARI PARAMITA KHEMASILI KOSALA DZULKIFLI DZULKIFLI DEBY INDAH SAPUTRI ENGGAR WIJAYANTI
author_facet	SWANDARI PARAMITA KHEMASILI KOSALA DZULKIFLI DZULKIFLI DEBY INDAH SAPUTRI ENGGAR WIJAYANTI
author_sort	SWANDARI PARAMITA
title	Anti-inflammatory activities of ethnomedicinal plants from Dayak Abai in North Kalimantan, Indonesia
title_short	Anti-inflammatory activities of ethnomedicinal plants from Dayak Abai in North Kalimantan, Indonesia
title_full	Anti-inflammatory activities of ethnomedicinal plants from Dayak Abai in North Kalimantan, Indonesia
title_fullStr	Anti-inflammatory activities of ethnomedicinal plants from Dayak Abai in North Kalimantan, Indonesia
title_full_unstemmed	Anti-inflammatory activities of ethnomedicinal plants from Dayak Abai in North Kalimantan, Indonesia
title_sort	anti-inflammatory activities of ethnomedicinal plants from dayak abai in north kalimantan, indonesia
publisher	MBI & UNS Solo
publishDate	2017
url	https://doaj.org/article/2bcb5bffe51049158ace0335c9a3c136
work_keys_str_mv	AT swandariparamita antiinflammatoryactivitiesofethnomedicinalplantsfromdayakabaiinnorthkalimantanindonesia AT khemasilikosala antiinflammatoryactivitiesofethnomedicinalplantsfromdayakabaiinnorthkalimantanindonesia AT dzulkiflidzulkifli antiinflammatoryactivitiesofethnomedicinalplantsfromdayakabaiinnorthkalimantanindonesia AT debyindahsaputri antiinflammatoryactivitiesofethnomedicinalplantsfromdayakabaiinnorthkalimantanindonesia AT enggarwijayanti antiinflammatoryactivitiesofethnomedicinalplantsfromdayakabaiinnorthkalimantanindonesia
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Anti-inflammatory activities of ethnomedicinal plants from Dayak Abai in North Kalimantan, Indonesia

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