Prophylactic postoperative ketorolac improves outcomes in diabetic patients assigned for cataract surgery

Moataz F Elsawy, Nermine Badawi, Hany A KhairyOphthalmology Department, Menoufia University Hospital, Menoufia, EgyptObjective: To evaluate the prophylactic role of topical non-steroidal anti-inflammatory drugs in reducing the incidence of central macular edema (CME) in diabetic eyes post-cataract s...

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Autores principales:	Elsawy MF, Badawi N, Khairy HA
Formato:	article
Lenguaje:	EN
Publicado:	Dove Medical Press 2013
Materias:	Ophthalmology RE1-994
Acceso en línea:	https://doaj.org/article/2bd7c27063f84e6482e7aadca7bb9848
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spelling	oai:doaj.org-article:2bd7c27063f84e6482e7aadca7bb98482021-12-02T01:19:23ZProphylactic postoperative ketorolac improves outcomes in diabetic patients assigned for cataract surgery1177-54671177-5483https://doaj.org/article/2bd7c27063f84e6482e7aadca7bb98482013-06-01T00:00:00Zhttp://www.dovepress.com/prophylactic-postoperative-ketorolac-improves-outcomes-in-diabetic-pat-a13437https://doaj.org/toc/1177-5467https://doaj.org/toc/1177-5483Moataz F Elsawy, Nermine Badawi, Hany A KhairyOphthalmology Department, Menoufia University Hospital, Menoufia, EgyptObjective: To evaluate the prophylactic role of topical non-steroidal anti-inflammatory drugs in reducing the incidence of central macular edema (CME) in diabetic eyes post-cataract surgery.Patients and methods: This study included 86 eyes (70 patients) with high risk characteristics for the development of CME after cataract surgery. All patients underwent phacoemulsification and intraocular lens implantation. Patients were divided into two equal groups (n = 43 [eyes]): a control group given topical dexamethasone 0.1%, four times/day for 12 weeks postoperatively and a study group given topical ketorolac tromethamine 0.4% twice daily in addition to topical dexamethasone 0.1% four times daily for 12 weeks. Patients were examined at 3, 6, and 12 weeks postoperatively for evaluation of CME development. The main study outcome was the change in the retinal fovea thickness measured with ocular coherence topography.Results: Ten eyes developed CME (11.6%); eight eyes in the control group and only two eyes in the study group. Mean retinal fovea thickness was significantly higher in the control group compared to the study group. Moreover, eyes of the control group developed CME significantly earlier than those of the study group.Conclusion: Prophylactic postoperative ketorolac 0.4% may have a role in reducing the frequency and severity of CME in diabetic eyes post-cataract surgery.Keywords: diabetes mellitus, cataract surgery, central macular edema, ketorolac, dexamethasoneElsawy MFBadawi NKhairy HADove Medical PressarticleOphthalmologyRE1-994ENClinical Ophthalmology, Vol 2013, Iss default, Pp 1245-1249 (2013)
institution	DOAJ
collection	DOAJ
language	EN
topic	Ophthalmology RE1-994
spellingShingle	Ophthalmology RE1-994 Elsawy MF Badawi N Khairy HA Prophylactic postoperative ketorolac improves outcomes in diabetic patients assigned for cataract surgery
description	Moataz F Elsawy, Nermine Badawi, Hany A KhairyOphthalmology Department, Menoufia University Hospital, Menoufia, EgyptObjective: To evaluate the prophylactic role of topical non-steroidal anti-inflammatory drugs in reducing the incidence of central macular edema (CME) in diabetic eyes post-cataract surgery.Patients and methods: This study included 86 eyes (70 patients) with high risk characteristics for the development of CME after cataract surgery. All patients underwent phacoemulsification and intraocular lens implantation. Patients were divided into two equal groups (n = 43 [eyes]): a control group given topical dexamethasone 0.1%, four times/day for 12 weeks postoperatively and a study group given topical ketorolac tromethamine 0.4% twice daily in addition to topical dexamethasone 0.1% four times daily for 12 weeks. Patients were examined at 3, 6, and 12 weeks postoperatively for evaluation of CME development. The main study outcome was the change in the retinal fovea thickness measured with ocular coherence topography.Results: Ten eyes developed CME (11.6%); eight eyes in the control group and only two eyes in the study group. Mean retinal fovea thickness was significantly higher in the control group compared to the study group. Moreover, eyes of the control group developed CME significantly earlier than those of the study group.Conclusion: Prophylactic postoperative ketorolac 0.4% may have a role in reducing the frequency and severity of CME in diabetic eyes post-cataract surgery.Keywords: diabetes mellitus, cataract surgery, central macular edema, ketorolac, dexamethasone
format	article
author	Elsawy MF Badawi N Khairy HA
author_facet	Elsawy MF Badawi N Khairy HA
author_sort	Elsawy MF
title	Prophylactic postoperative ketorolac improves outcomes in diabetic patients assigned for cataract surgery
title_short	Prophylactic postoperative ketorolac improves outcomes in diabetic patients assigned for cataract surgery
title_full	Prophylactic postoperative ketorolac improves outcomes in diabetic patients assigned for cataract surgery
title_fullStr	Prophylactic postoperative ketorolac improves outcomes in diabetic patients assigned for cataract surgery
title_full_unstemmed	Prophylactic postoperative ketorolac improves outcomes in diabetic patients assigned for cataract surgery
title_sort	prophylactic postoperative ketorolac improves outcomes in diabetic patients assigned for cataract surgery
publisher	Dove Medical Press
publishDate	2013
url	https://doaj.org/article/2bd7c27063f84e6482e7aadca7bb9848
work_keys_str_mv	AT elsawymf prophylacticpostoperativeketorolacimprovesoutcomesindiabeticpatientsassignedforcataractsurgery AT badawin prophylacticpostoperativeketorolacimprovesoutcomesindiabeticpatientsassignedforcataractsurgery AT khairyha prophylacticpostoperativeketorolacimprovesoutcomesindiabeticpatientsassignedforcataractsurgery
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Prophylactic postoperative ketorolac improves outcomes in diabetic patients assigned for cataract surgery

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