Structure of the error-prone DNA ligase of African swine fever virus identifies critical active site residues

Structure of the error-prone DNA ligase of African swine fever virus identifies critical active site residues

The DNA ligase of African swine fever virus is one of the most error-prone ligases identified to date, but underlying molecular details are lacking. Here, Chen et al. report four AsfvLIG:DNA structures and identify a unique N-terminal domain and four unique active site residues that are crucial for...

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Autores principales: Yiqing Chen, Hehua Liu, Chun Yang, Yanqing Gao, Xiang Yu, Xi Chen, Ruixue Cui, Lina Zheng, Suhua Li, Xuhang Li, Jinbiao Ma, Zhen Huang, Jixi Li, Jianhua Gan
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2019
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Science
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Acceso en línea:https://doaj.org/article/2bedf69d630b4905bf64d70caac45ee1
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