SEROLOGICAL DIAGNOSIS OF MODERN CHOLERA USING LIPOSOMAL ENTEROTOXIC DIAGNOSTICUM IN COMPLEMENT FIXATION TEST

Abstract. The possibility of serological diagnosis of cholera using cholera enterotoxic diagnostics kit in complement fixation test to detect anti-enterotoxic antibodies in sera of patients with cholera caused by hybrid variants of the El Tor biovar has been demonstrated. In patients with mild cours...

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Autores principales:	I. V. Savelyeva, V. E. Bezsmertnyj, V. N. Savelyev, Yu. M. Fedorov, C. M. Ivanova, V. V. Ivannikov
Formato:	article
Lenguaje:	RU
Publicado:	Sankt-Peterburg : NIIÈM imeni Pastera 2014
Materias:	serological diagnosis cholera liposomal diagnosticum direct complement fixation test Infectious and parasitic diseases RC109-216
Acceso en línea:	https://doaj.org/article/2bf1dd8b3b804d5a85b6ecf21f44ca5a
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spelling	oai:doaj.org-article:2bf1dd8b3b804d5a85b6ecf21f44ca5a2021-11-22T07:09:46ZSEROLOGICAL DIAGNOSIS OF MODERN CHOLERA USING LIPOSOMAL ENTEROTOXIC DIAGNOSTICUM IN COMPLEMENT FIXATION TEST2220-76192313-739810.15789/2220-7619-2013-3-285-288https://doaj.org/article/2bf1dd8b3b804d5a85b6ecf21f44ca5a2014-07-01T00:00:00Zhttps://www.iimmun.ru/iimm/article/view/177https://doaj.org/toc/2220-7619https://doaj.org/toc/2313-7398Abstract. The possibility of serological diagnosis of cholera using cholera enterotoxic diagnostics kit in complement fixation test to detect anti-enterotoxic antibodies in sera of patients with cholera caused by hybrid variants of the El Tor biovar has been demonstrated. In patients with mild course of cholera anti-enterotoxic antibodies were detected in titres 1:50 and 1:200 in paired sera obtained on the 7th and 14th days of disease, respectively (fourfold titre increase). In patients with the course of medium severity 32-fold titre increase was recorded from the titre 1:100 in serum obtained on the fifth day of disease till the titre 1:3200 — on the twelfth day of disease. Antibodies titers reached 1:1600 and 1:800 were revealed in two medium course patients (adult and infant of 10 months) on the sixth day of disease.I. V. SavelyevaV. E. BezsmertnyjV. N. SavelyevYu. M. FedorovC. M. IvanovaV. V. IvannikovSankt-Peterburg : NIIÈM imeni Pasteraarticleserological diagnosischoleraliposomal diagnosticumdirect complement fixation testInfectious and parasitic diseasesRC109-216RUInfekciâ i Immunitet, Vol 3, Iss 3, Pp 285-288 (2014)
institution	DOAJ
collection	DOAJ
language	RU
topic	serological diagnosis cholera liposomal diagnosticum direct complement fixation test Infectious and parasitic diseases RC109-216
spellingShingle	serological diagnosis cholera liposomal diagnosticum direct complement fixation test Infectious and parasitic diseases RC109-216 I. V. Savelyeva V. E. Bezsmertnyj V. N. Savelyev Yu. M. Fedorov C. M. Ivanova V. V. Ivannikov SEROLOGICAL DIAGNOSIS OF MODERN CHOLERA USING LIPOSOMAL ENTEROTOXIC DIAGNOSTICUM IN COMPLEMENT FIXATION TEST
description	Abstract. The possibility of serological diagnosis of cholera using cholera enterotoxic diagnostics kit in complement fixation test to detect anti-enterotoxic antibodies in sera of patients with cholera caused by hybrid variants of the El Tor biovar has been demonstrated. In patients with mild course of cholera anti-enterotoxic antibodies were detected in titres 1:50 and 1:200 in paired sera obtained on the 7th and 14th days of disease, respectively (fourfold titre increase). In patients with the course of medium severity 32-fold titre increase was recorded from the titre 1:100 in serum obtained on the fifth day of disease till the titre 1:3200 — on the twelfth day of disease. Antibodies titers reached 1:1600 and 1:800 were revealed in two medium course patients (adult and infant of 10 months) on the sixth day of disease.
format	article
author	I. V. Savelyeva V. E. Bezsmertnyj V. N. Savelyev Yu. M. Fedorov C. M. Ivanova V. V. Ivannikov
author_facet	I. V. Savelyeva V. E. Bezsmertnyj V. N. Savelyev Yu. M. Fedorov C. M. Ivanova V. V. Ivannikov
author_sort	I. V. Savelyeva
title	SEROLOGICAL DIAGNOSIS OF MODERN CHOLERA USING LIPOSOMAL ENTEROTOXIC DIAGNOSTICUM IN COMPLEMENT FIXATION TEST
title_short	SEROLOGICAL DIAGNOSIS OF MODERN CHOLERA USING LIPOSOMAL ENTEROTOXIC DIAGNOSTICUM IN COMPLEMENT FIXATION TEST
title_full	SEROLOGICAL DIAGNOSIS OF MODERN CHOLERA USING LIPOSOMAL ENTEROTOXIC DIAGNOSTICUM IN COMPLEMENT FIXATION TEST
title_fullStr	SEROLOGICAL DIAGNOSIS OF MODERN CHOLERA USING LIPOSOMAL ENTEROTOXIC DIAGNOSTICUM IN COMPLEMENT FIXATION TEST
title_full_unstemmed	SEROLOGICAL DIAGNOSIS OF MODERN CHOLERA USING LIPOSOMAL ENTEROTOXIC DIAGNOSTICUM IN COMPLEMENT FIXATION TEST
title_sort	serological diagnosis of modern cholera using liposomal enterotoxic diagnosticum in complement fixation test
publisher	Sankt-Peterburg : NIIÈM imeni Pastera
publishDate	2014
url	https://doaj.org/article/2bf1dd8b3b804d5a85b6ecf21f44ca5a
work_keys_str_mv	AT ivsavelyeva serologicaldiagnosisofmoderncholerausingliposomalenterotoxicdiagnosticumincomplementfixationtest AT vebezsmertnyj serologicaldiagnosisofmoderncholerausingliposomalenterotoxicdiagnosticumincomplementfixationtest AT vnsavelyev serologicaldiagnosisofmoderncholerausingliposomalenterotoxicdiagnosticumincomplementfixationtest AT yumfedorov serologicaldiagnosisofmoderncholerausingliposomalenterotoxicdiagnosticumincomplementfixationtest AT cmivanova serologicaldiagnosisofmoderncholerausingliposomalenterotoxicdiagnosticumincomplementfixationtest AT vvivannikov serologicaldiagnosisofmoderncholerausingliposomalenterotoxicdiagnosticumincomplementfixationtest
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SEROLOGICAL DIAGNOSIS OF MODERN CHOLERA USING LIPOSOMAL ENTEROTOXIC DIAGNOSTICUM IN COMPLEMENT FIXATION TEST

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