Mobile-Genetic-Element-Encoded Hypertolerance to Copper Protects <named-content content-type="genus-species">Staphylococcus aureus</named-content> from Killing by Host Phagocytes

Mobile-Genetic-Element-Encoded Hypertolerance to Copper Protects <named-content content-type="genus-species">Staphylococcus aureus</named-content> from Killing by Host Phagocytes

ABSTRACT Pathogens are exposed to toxic levels of copper during infection, and copper tolerance may be a general virulence mechanism used by bacteria to resist host defenses. In support of this, inactivation of copper exporter genes has been found to reduce the virulence of bacterial pathogens in vi...

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Autores principales: Marta Zapotoczna, Gustavo P. Riboldi, Ahmed M. Moustafa, Elizabeth Dickson, Apurva Narechania, Julie A. Morrissey, Paul J. Planet, Matthew T. G. Holden, Kevin J. Waldron, Joan A. Geoghegan
Formato: article
Lenguaje:EN
Publicado: American Society for Microbiology 2018
Materias:
MRSA
P-type ATPase
Staphylococcus aureus
copper tolerance
macrophages
metals
Microbiology
QR1-502
Acceso en línea:https://doaj.org/article/2bf73d0d0ecc4842a392be8e865a0c11
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