BET inhibitor suppresses migration of human hepatocellular carcinoma by inhibiting SMARCA4

BET inhibitor suppresses migration of human hepatocellular carcinoma by inhibiting SMARCA4

Abstract Hepatocellular carcinoma (HCC) is one of the most prevalent and poorly responsive cancers worldwide. Bromodomain and extraterminal (BET) inhibitors, such as JQ1 and OTX-015, inhibit BET protein binding to acetylated residues in histones. However, the physiological mechanisms and regulatory...

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Autores principales: Hae In Choi, Ga Yeong An, Mina Baek, Eunyoung Yoo, Jin Choul Chai, Young Seek Lee, Kyoung Hwa Jung, Young Gyu Chai
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2021
Materias:
Medicine
R
Science
Q
Acceso en línea:https://doaj.org/article/2bf925a7b1f44275898bb8e721a341c7
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