Ebola virus VP24 interacts with NP to facilitate nucleocapsid assembly and genome packaging

Ebola virus VP24 interacts with NP to facilitate nucleocapsid assembly and genome packaging

Abstract Ebola virus causes devastating hemorrhagic fever outbreaks for which no approved therapeutic exists. The viral nucleocapsid, which is minimally composed of the proteins NP, VP35, and VP24, represents an attractive target for drug development; however, the molecular determinants that govern...

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Autores principales: Logan Banadyga, Thomas Hoenen, Xavier Ambroggio, Eric Dunham, Allison Groseth, Hideki Ebihara
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2017
Materias:
Medicine
R
Science
Q
Acceso en línea:https://doaj.org/article/2bfc0c3ea9f142f7be19ae38b181ed11
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