Ep400 deficiency in Schwann cells causes persistent expression of early developmental regulators and peripheral neuropathy

The Ep400 chromatin remodeler determines genomic distribution of variant histones. In the current study, the authors show that loss of Ep400 in Schwann cells leads to aberrant expression of developmental regulators, and a peripheral neuropathy phenotype.

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Autores principales: Franziska Fröb, Elisabeth Sock, Ernst. R. Tamm, Anna-Lena Saur, Simone Hillgärtner, Trevor J. Williams, Toshihiro Fujii, Rikiro Fukunaga, Michael Wegner
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2019
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Acceso en línea:https://doaj.org/article/2c01dc5a25984a1dbe35317ab8b430f2
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