The acetyllysine reader BRD3R promotes human nuclear reprogramming and regulates mitosis

The reprogramming of fibroblasts to pluripotent stem cells has been well documented but there is interest in identifying additional factors involved. Here, the authors perform a screen of human kinases and show that the bromodomain protein, BRD3R, can promote reprogramming and suggest a role for thi...

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Autores principales:	Zhicheng Shao, Ruowen Zhang, Alireza Khodadadi-Jamayran, Bo Chen, Michael R. Crowley, Muhamad A. Festok, David K. Crossman, Tim M. Townes, Kejin Hu
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2016
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/2c03150be20b40b99365bc38d4dfcd63
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spelling	oai:doaj.org-article:2c03150be20b40b99365bc38d4dfcd632021-12-02T14:39:29ZThe acetyllysine reader BRD3R promotes human nuclear reprogramming and regulates mitosis10.1038/ncomms108692041-1723https://doaj.org/article/2c03150be20b40b99365bc38d4dfcd632016-03-01T00:00:00Zhttps://doi.org/10.1038/ncomms10869https://doaj.org/toc/2041-1723The reprogramming of fibroblasts to pluripotent stem cells has been well documented but there is interest in identifying additional factors involved. Here, the authors perform a screen of human kinases and show that the bromodomain protein, BRD3R, can promote reprogramming and suggest a role for this factor in regulating mitosis.Zhicheng ShaoRuowen ZhangAlireza Khodadadi-JamayranBo ChenMichael R. CrowleyMuhamad A. FestokDavid K. CrossmanTim M. TownesKejin HuNature PortfolioarticleScienceQENNature Communications, Vol 7, Iss 1, Pp 1-15 (2016)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Zhicheng Shao Ruowen Zhang Alireza Khodadadi-Jamayran Bo Chen Michael R. Crowley Muhamad A. Festok David K. Crossman Tim M. Townes Kejin Hu The acetyllysine reader BRD3R promotes human nuclear reprogramming and regulates mitosis
description	The reprogramming of fibroblasts to pluripotent stem cells has been well documented but there is interest in identifying additional factors involved. Here, the authors perform a screen of human kinases and show that the bromodomain protein, BRD3R, can promote reprogramming and suggest a role for this factor in regulating mitosis.
format	article
author	Zhicheng Shao Ruowen Zhang Alireza Khodadadi-Jamayran Bo Chen Michael R. Crowley Muhamad A. Festok David K. Crossman Tim M. Townes Kejin Hu
author_facet	Zhicheng Shao Ruowen Zhang Alireza Khodadadi-Jamayran Bo Chen Michael R. Crowley Muhamad A. Festok David K. Crossman Tim M. Townes Kejin Hu
author_sort	Zhicheng Shao
title	The acetyllysine reader BRD3R promotes human nuclear reprogramming and regulates mitosis
title_short	The acetyllysine reader BRD3R promotes human nuclear reprogramming and regulates mitosis
title_full	The acetyllysine reader BRD3R promotes human nuclear reprogramming and regulates mitosis
title_fullStr	The acetyllysine reader BRD3R promotes human nuclear reprogramming and regulates mitosis
title_full_unstemmed	The acetyllysine reader BRD3R promotes human nuclear reprogramming and regulates mitosis
title_sort	acetyllysine reader brd3r promotes human nuclear reprogramming and regulates mitosis
publisher	Nature Portfolio
publishDate	2016
url	https://doaj.org/article/2c03150be20b40b99365bc38d4dfcd63
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The acetyllysine reader BRD3R promotes human nuclear reprogramming and regulates mitosis

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