MicroED structure of the NaK ion channel reveals a Na+ partition process into the selectivity filter
Through a MicroED structure of NaK ion channel, Shian Liu and Tamir Gonen identify a process of dilation coupled with Na+ movement, providing mechanistic insights into ion conduction and gating. This study lays the ground work for future studies using MicroED in membrane protein biophysics.
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2018
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oai:doaj.org-article:2c057e77a10e4c9d9c143cffaba4f1102021-12-02T12:30:50ZMicroED structure of the NaK ion channel reveals a Na+ partition process into the selectivity filter10.1038/s42003-018-0040-82399-3642https://doaj.org/article/2c057e77a10e4c9d9c143cffaba4f1102018-05-01T00:00:00Zhttps://doi.org/10.1038/s42003-018-0040-8https://doaj.org/toc/2399-3642Through a MicroED structure of NaK ion channel, Shian Liu and Tamir Gonen identify a process of dilation coupled with Na+ movement, providing mechanistic insights into ion conduction and gating. This study lays the ground work for future studies using MicroED in membrane protein biophysics.Shian LiuTamir GonenNature PortfolioarticleBiology (General)QH301-705.5ENCommunications Biology, Vol 1, Iss 1, Pp 1-6 (2018) |
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DOAJ |
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Biology (General) QH301-705.5 |
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Biology (General) QH301-705.5 Shian Liu Tamir Gonen MicroED structure of the NaK ion channel reveals a Na+ partition process into the selectivity filter |
description |
Through a MicroED structure of NaK ion channel, Shian Liu and Tamir Gonen identify a process of dilation coupled with Na+ movement, providing mechanistic insights into ion conduction and gating. This study lays the ground work for future studies using MicroED in membrane protein biophysics. |
format |
article |
author |
Shian Liu Tamir Gonen |
author_facet |
Shian Liu Tamir Gonen |
author_sort |
Shian Liu |
title |
MicroED structure of the NaK ion channel reveals a Na+ partition process into the selectivity filter |
title_short |
MicroED structure of the NaK ion channel reveals a Na+ partition process into the selectivity filter |
title_full |
MicroED structure of the NaK ion channel reveals a Na+ partition process into the selectivity filter |
title_fullStr |
MicroED structure of the NaK ion channel reveals a Na+ partition process into the selectivity filter |
title_full_unstemmed |
MicroED structure of the NaK ion channel reveals a Na+ partition process into the selectivity filter |
title_sort |
microed structure of the nak ion channel reveals a na+ partition process into the selectivity filter |
publisher |
Nature Portfolio |
publishDate |
2018 |
url |
https://doaj.org/article/2c057e77a10e4c9d9c143cffaba4f110 |
work_keys_str_mv |
AT shianliu microedstructureofthenakionchannelrevealsanapartitionprocessintotheselectivityfilter AT tamirgonen microedstructureofthenakionchannelrevealsanapartitionprocessintotheselectivityfilter |
_version_ |
1718394324637450240 |