MicroED structure of the NaK ion channel reveals a Na+ partition process into the selectivity filter

Through a MicroED structure of NaK ion channel, Shian Liu and Tamir Gonen identify a process of dilation coupled with Na+ movement, providing mechanistic insights into ion conduction and gating. This study lays the ground work for future studies using MicroED in membrane protein biophysics.

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Autores principales: Shian Liu, Tamir Gonen
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2018
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Acceso en línea:https://doaj.org/article/2c057e77a10e4c9d9c143cffaba4f110
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spelling oai:doaj.org-article:2c057e77a10e4c9d9c143cffaba4f1102021-12-02T12:30:50ZMicroED structure of the NaK ion channel reveals a Na+ partition process into the selectivity filter10.1038/s42003-018-0040-82399-3642https://doaj.org/article/2c057e77a10e4c9d9c143cffaba4f1102018-05-01T00:00:00Zhttps://doi.org/10.1038/s42003-018-0040-8https://doaj.org/toc/2399-3642Through a MicroED structure of NaK ion channel, Shian Liu and Tamir Gonen identify a process of dilation coupled with Na+ movement, providing mechanistic insights into ion conduction and gating. This study lays the ground work for future studies using MicroED in membrane protein biophysics.Shian LiuTamir GonenNature PortfolioarticleBiology (General)QH301-705.5ENCommunications Biology, Vol 1, Iss 1, Pp 1-6 (2018)
institution DOAJ
collection DOAJ
language EN
topic Biology (General)
QH301-705.5
spellingShingle Biology (General)
QH301-705.5
Shian Liu
Tamir Gonen
MicroED structure of the NaK ion channel reveals a Na+ partition process into the selectivity filter
description Through a MicroED structure of NaK ion channel, Shian Liu and Tamir Gonen identify a process of dilation coupled with Na+ movement, providing mechanistic insights into ion conduction and gating. This study lays the ground work for future studies using MicroED in membrane protein biophysics.
format article
author Shian Liu
Tamir Gonen
author_facet Shian Liu
Tamir Gonen
author_sort Shian Liu
title MicroED structure of the NaK ion channel reveals a Na+ partition process into the selectivity filter
title_short MicroED structure of the NaK ion channel reveals a Na+ partition process into the selectivity filter
title_full MicroED structure of the NaK ion channel reveals a Na+ partition process into the selectivity filter
title_fullStr MicroED structure of the NaK ion channel reveals a Na+ partition process into the selectivity filter
title_full_unstemmed MicroED structure of the NaK ion channel reveals a Na+ partition process into the selectivity filter
title_sort microed structure of the nak ion channel reveals a na+ partition process into the selectivity filter
publisher Nature Portfolio
publishDate 2018
url https://doaj.org/article/2c057e77a10e4c9d9c143cffaba4f110
work_keys_str_mv AT shianliu microedstructureofthenakionchannelrevealsanapartitionprocessintotheselectivityfilter
AT tamirgonen microedstructureofthenakionchannelrevealsanapartitionprocessintotheselectivityfilter
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