Prefrontal projections to the thalamic nucleus reuniens mediate fear extinction

Previous work has shown that the thalamic nucleus reuniens (RE) is involved in memory and emotion. Here the authors report that the RE and its inputs from the medial prefrontal cortex are indispensable for the top-down inhibition of fear memories after extinction.

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Autores principales:	Karthik R. Ramanathan, Jingji Jin, Thomas F. Giustino, Martin R. Payne, Stephen Maren
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2018
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/2c05d4890864491b86de7d7904a2ad25
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spelling	oai:doaj.org-article:2c05d4890864491b86de7d7904a2ad252021-12-02T17:31:45ZPrefrontal projections to the thalamic nucleus reuniens mediate fear extinction10.1038/s41467-018-06970-z2041-1723https://doaj.org/article/2c05d4890864491b86de7d7904a2ad252018-10-01T00:00:00Zhttps://doi.org/10.1038/s41467-018-06970-zhttps://doaj.org/toc/2041-1723Previous work has shown that the thalamic nucleus reuniens (RE) is involved in memory and emotion. Here the authors report that the RE and its inputs from the medial prefrontal cortex are indispensable for the top-down inhibition of fear memories after extinction.Karthik R. RamanathanJingji JinThomas F. GiustinoMartin R. PayneStephen MarenNature PortfolioarticleScienceQENNature Communications, Vol 9, Iss 1, Pp 1-12 (2018)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Karthik R. Ramanathan Jingji Jin Thomas F. Giustino Martin R. Payne Stephen Maren Prefrontal projections to the thalamic nucleus reuniens mediate fear extinction
description	Previous work has shown that the thalamic nucleus reuniens (RE) is involved in memory and emotion. Here the authors report that the RE and its inputs from the medial prefrontal cortex are indispensable for the top-down inhibition of fear memories after extinction.
format	article
author	Karthik R. Ramanathan Jingji Jin Thomas F. Giustino Martin R. Payne Stephen Maren
author_facet	Karthik R. Ramanathan Jingji Jin Thomas F. Giustino Martin R. Payne Stephen Maren
author_sort	Karthik R. Ramanathan
title	Prefrontal projections to the thalamic nucleus reuniens mediate fear extinction
title_short	Prefrontal projections to the thalamic nucleus reuniens mediate fear extinction
title_full	Prefrontal projections to the thalamic nucleus reuniens mediate fear extinction
title_fullStr	Prefrontal projections to the thalamic nucleus reuniens mediate fear extinction
title_full_unstemmed	Prefrontal projections to the thalamic nucleus reuniens mediate fear extinction
title_sort	prefrontal projections to the thalamic nucleus reuniens mediate fear extinction
publisher	Nature Portfolio
publishDate	2018
url	https://doaj.org/article/2c05d4890864491b86de7d7904a2ad25
work_keys_str_mv	AT karthikrramanathan prefrontalprojectionstothethalamicnucleusreuniensmediatefearextinction AT jingjijin prefrontalprojectionstothethalamicnucleusreuniensmediatefearextinction AT thomasfgiustino prefrontalprojectionstothethalamicnucleusreuniensmediatefearextinction AT martinrpayne prefrontalprojectionstothethalamicnucleusreuniensmediatefearextinction AT stephenmaren prefrontalprojectionstothethalamicnucleusreuniensmediatefearextinction
_version_	1718380480080904192

Prefrontal projections to the thalamic nucleus reuniens mediate fear extinction

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