klf2a couples mechanotransduction and zebrafish valve morphogenesis through fibronectin synthesis

In the developing heart, blood flow transmits mechanical signals to progenitor cells that ultimately leads to valve formation. Here, the authors identify the origin of the valve progenitor cells and fibronectin1bas a transcriptional target of the mechanotransduced signals responsible for valve forma...

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Autores principales: Emily Steed, Nathalie Faggianelli, Stéphane Roth, Caroline Ramspacher, Jean-Paul Concordet, Julien Vermot
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2016
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Acceso en línea:https://doaj.org/article/2c0831bd19cb4f7abaf7a6a2a2d5adbc
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spelling oai:doaj.org-article:2c0831bd19cb4f7abaf7a6a2a2d5adbc2021-12-02T15:33:48Zklf2a couples mechanotransduction and zebrafish valve morphogenesis through fibronectin synthesis10.1038/ncomms116462041-1723https://doaj.org/article/2c0831bd19cb4f7abaf7a6a2a2d5adbc2016-05-01T00:00:00Zhttps://doi.org/10.1038/ncomms11646https://doaj.org/toc/2041-1723In the developing heart, blood flow transmits mechanical signals to progenitor cells that ultimately leads to valve formation. Here, the authors identify the origin of the valve progenitor cells and fibronectin1bas a transcriptional target of the mechanotransduced signals responsible for valve formation.Emily SteedNathalie FaggianelliStéphane RothCaroline RamspacherJean-Paul ConcordetJulien VermotNature PortfolioarticleScienceQENNature Communications, Vol 7, Iss 1, Pp 1-14 (2016)
institution DOAJ
collection DOAJ
language EN
topic Science
Q
spellingShingle Science
Q
Emily Steed
Nathalie Faggianelli
Stéphane Roth
Caroline Ramspacher
Jean-Paul Concordet
Julien Vermot
klf2a couples mechanotransduction and zebrafish valve morphogenesis through fibronectin synthesis
description In the developing heart, blood flow transmits mechanical signals to progenitor cells that ultimately leads to valve formation. Here, the authors identify the origin of the valve progenitor cells and fibronectin1bas a transcriptional target of the mechanotransduced signals responsible for valve formation.
format article
author Emily Steed
Nathalie Faggianelli
Stéphane Roth
Caroline Ramspacher
Jean-Paul Concordet
Julien Vermot
author_facet Emily Steed
Nathalie Faggianelli
Stéphane Roth
Caroline Ramspacher
Jean-Paul Concordet
Julien Vermot
author_sort Emily Steed
title klf2a couples mechanotransduction and zebrafish valve morphogenesis through fibronectin synthesis
title_short klf2a couples mechanotransduction and zebrafish valve morphogenesis through fibronectin synthesis
title_full klf2a couples mechanotransduction and zebrafish valve morphogenesis through fibronectin synthesis
title_fullStr klf2a couples mechanotransduction and zebrafish valve morphogenesis through fibronectin synthesis
title_full_unstemmed klf2a couples mechanotransduction and zebrafish valve morphogenesis through fibronectin synthesis
title_sort klf2a couples mechanotransduction and zebrafish valve morphogenesis through fibronectin synthesis
publisher Nature Portfolio
publishDate 2016
url https://doaj.org/article/2c0831bd19cb4f7abaf7a6a2a2d5adbc
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AT stephaneroth klf2acouplesmechanotransductionandzebrafishvalvemorphogenesisthroughfibronectinsynthesis
AT carolineramspacher klf2acouplesmechanotransductionandzebrafishvalvemorphogenesisthroughfibronectinsynthesis
AT jeanpaulconcordet klf2acouplesmechanotransductionandzebrafishvalvemorphogenesisthroughfibronectinsynthesis
AT julienvermot klf2acouplesmechanotransductionandzebrafishvalvemorphogenesisthroughfibronectinsynthesis
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