klf2a couples mechanotransduction and zebrafish valve morphogenesis through fibronectin synthesis
In the developing heart, blood flow transmits mechanical signals to progenitor cells that ultimately leads to valve formation. Here, the authors identify the origin of the valve progenitor cells and fibronectin1bas a transcriptional target of the mechanotransduced signals responsible for valve forma...
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2016
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oai:doaj.org-article:2c0831bd19cb4f7abaf7a6a2a2d5adbc2021-12-02T15:33:48Zklf2a couples mechanotransduction and zebrafish valve morphogenesis through fibronectin synthesis10.1038/ncomms116462041-1723https://doaj.org/article/2c0831bd19cb4f7abaf7a6a2a2d5adbc2016-05-01T00:00:00Zhttps://doi.org/10.1038/ncomms11646https://doaj.org/toc/2041-1723In the developing heart, blood flow transmits mechanical signals to progenitor cells that ultimately leads to valve formation. Here, the authors identify the origin of the valve progenitor cells and fibronectin1bas a transcriptional target of the mechanotransduced signals responsible for valve formation.Emily SteedNathalie FaggianelliStéphane RothCaroline RamspacherJean-Paul ConcordetJulien VermotNature PortfolioarticleScienceQENNature Communications, Vol 7, Iss 1, Pp 1-14 (2016) |
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Science Q Emily Steed Nathalie Faggianelli Stéphane Roth Caroline Ramspacher Jean-Paul Concordet Julien Vermot klf2a couples mechanotransduction and zebrafish valve morphogenesis through fibronectin synthesis |
description |
In the developing heart, blood flow transmits mechanical signals to progenitor cells that ultimately leads to valve formation. Here, the authors identify the origin of the valve progenitor cells and fibronectin1bas a transcriptional target of the mechanotransduced signals responsible for valve formation. |
format |
article |
author |
Emily Steed Nathalie Faggianelli Stéphane Roth Caroline Ramspacher Jean-Paul Concordet Julien Vermot |
author_facet |
Emily Steed Nathalie Faggianelli Stéphane Roth Caroline Ramspacher Jean-Paul Concordet Julien Vermot |
author_sort |
Emily Steed |
title |
klf2a couples mechanotransduction and zebrafish valve morphogenesis through fibronectin synthesis |
title_short |
klf2a couples mechanotransduction and zebrafish valve morphogenesis through fibronectin synthesis |
title_full |
klf2a couples mechanotransduction and zebrafish valve morphogenesis through fibronectin synthesis |
title_fullStr |
klf2a couples mechanotransduction and zebrafish valve morphogenesis through fibronectin synthesis |
title_full_unstemmed |
klf2a couples mechanotransduction and zebrafish valve morphogenesis through fibronectin synthesis |
title_sort |
klf2a couples mechanotransduction and zebrafish valve morphogenesis through fibronectin synthesis |
publisher |
Nature Portfolio |
publishDate |
2016 |
url |
https://doaj.org/article/2c0831bd19cb4f7abaf7a6a2a2d5adbc |
work_keys_str_mv |
AT emilysteed klf2acouplesmechanotransductionandzebrafishvalvemorphogenesisthroughfibronectinsynthesis AT nathaliefaggianelli klf2acouplesmechanotransductionandzebrafishvalvemorphogenesisthroughfibronectinsynthesis AT stephaneroth klf2acouplesmechanotransductionandzebrafishvalvemorphogenesisthroughfibronectinsynthesis AT carolineramspacher klf2acouplesmechanotransductionandzebrafishvalvemorphogenesisthroughfibronectinsynthesis AT jeanpaulconcordet klf2acouplesmechanotransductionandzebrafishvalvemorphogenesisthroughfibronectinsynthesis AT julienvermot klf2acouplesmechanotransductionandzebrafishvalvemorphogenesisthroughfibronectinsynthesis |
_version_ |
1718387012866670592 |