Induction of resident memory T cells enhances the efficacy of cancer vaccine

Resident memory T cells (Trm) are memory T cells that remain in tissue. Here, the authors show that induction of Trm cells is required for control of tumour growth following mucosal vaccination in mice bearing head and neck cancer and that Trm cells in human lung cancer correlates with a better surv...

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Autores principales:	Mevyn Nizard, Hélène Roussel, Mariana O. Diniz, Soumaya Karaki, Thi Tran, Thibault Voron, Estelle Dransart, Federico Sandoval, Marc Riquet, Bastien Rance, Elie Marcheteau, Elizabeth Fabre, Marion Mandavit, Magali Terme, Charlotte Blanc, Jean-Baptiste Escudie, Laure Gibault, Françoise Le Pimpec Barthes, Clemence Granier, Luis C. S. Ferreira, Cecile Badoual, Ludger Johannes, Eric Tartour
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2017
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/2c09610a4b334c25a37a0973fab8481f
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spelling	oai:doaj.org-article:2c09610a4b334c25a37a0973fab8481f2021-12-02T14:42:34ZInduction of resident memory T cells enhances the efficacy of cancer vaccine10.1038/ncomms152212041-1723https://doaj.org/article/2c09610a4b334c25a37a0973fab8481f2017-05-01T00:00:00Zhttps://doi.org/10.1038/ncomms15221https://doaj.org/toc/2041-1723Resident memory T cells (Trm) are memory T cells that remain in tissue. Here, the authors show that induction of Trm cells is required for control of tumour growth following mucosal vaccination in mice bearing head and neck cancer and that Trm cells in human lung cancer correlates with a better survival.Mevyn NizardHélène RousselMariana O. DinizSoumaya KarakiThi TranThibault VoronEstelle DransartFederico SandovalMarc RiquetBastien RanceElie MarcheteauElizabeth FabreMarion MandavitMagali TermeCharlotte BlancJean-Baptiste EscudieLaure GibaultFrançoise Le Pimpec BarthesClemence GranierLuis C. S. FerreiraCecile BadoualLudger JohannesEric TartourNature PortfolioarticleScienceQENNature Communications, Vol 8, Iss 1, Pp 1-11 (2017)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Mevyn Nizard Hélène Roussel Mariana O. Diniz Soumaya Karaki Thi Tran Thibault Voron Estelle Dransart Federico Sandoval Marc Riquet Bastien Rance Elie Marcheteau Elizabeth Fabre Marion Mandavit Magali Terme Charlotte Blanc Jean-Baptiste Escudie Laure Gibault Françoise Le Pimpec Barthes Clemence Granier Luis C. S. Ferreira Cecile Badoual Ludger Johannes Eric Tartour Induction of resident memory T cells enhances the efficacy of cancer vaccine
description	Resident memory T cells (Trm) are memory T cells that remain in tissue. Here, the authors show that induction of Trm cells is required for control of tumour growth following mucosal vaccination in mice bearing head and neck cancer and that Trm cells in human lung cancer correlates with a better survival.
format	article
author	Mevyn Nizard Hélène Roussel Mariana O. Diniz Soumaya Karaki Thi Tran Thibault Voron Estelle Dransart Federico Sandoval Marc Riquet Bastien Rance Elie Marcheteau Elizabeth Fabre Marion Mandavit Magali Terme Charlotte Blanc Jean-Baptiste Escudie Laure Gibault Françoise Le Pimpec Barthes Clemence Granier Luis C. S. Ferreira Cecile Badoual Ludger Johannes Eric Tartour
author_facet	Mevyn Nizard Hélène Roussel Mariana O. Diniz Soumaya Karaki Thi Tran Thibault Voron Estelle Dransart Federico Sandoval Marc Riquet Bastien Rance Elie Marcheteau Elizabeth Fabre Marion Mandavit Magali Terme Charlotte Blanc Jean-Baptiste Escudie Laure Gibault Françoise Le Pimpec Barthes Clemence Granier Luis C. S. Ferreira Cecile Badoual Ludger Johannes Eric Tartour
author_sort	Mevyn Nizard
title	Induction of resident memory T cells enhances the efficacy of cancer vaccine
title_short	Induction of resident memory T cells enhances the efficacy of cancer vaccine
title_full	Induction of resident memory T cells enhances the efficacy of cancer vaccine
title_fullStr	Induction of resident memory T cells enhances the efficacy of cancer vaccine
title_full_unstemmed	Induction of resident memory T cells enhances the efficacy of cancer vaccine
title_sort	induction of resident memory t cells enhances the efficacy of cancer vaccine
publisher	Nature Portfolio
publishDate	2017
url	https://doaj.org/article/2c09610a4b334c25a37a0973fab8481f
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Induction of resident memory T cells enhances the efficacy of cancer vaccine

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