Ethanol abolishes vigilance-dependent astroglia network activation in mice by inhibiting norepinephrine release
The effects of norepinephrine on sensory processing in cortical networks are altered by recreational drugs like ethanol. The authors show that ethanol suppresses the activation of astrocytes by inhibiting norepinephrine release which may contribute to the cognitive effects of alcohol intoxication.
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Nature Portfolio
2020
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oai:doaj.org-article:2c1ad302fc1a4bc19e4ebac3ad4638f32021-12-02T15:39:24ZEthanol abolishes vigilance-dependent astroglia network activation in mice by inhibiting norepinephrine release10.1038/s41467-020-19475-52041-1723https://doaj.org/article/2c1ad302fc1a4bc19e4ebac3ad4638f32020-12-01T00:00:00Zhttps://doi.org/10.1038/s41467-020-19475-5https://doaj.org/toc/2041-1723The effects of norepinephrine on sensory processing in cortical networks are altered by recreational drugs like ethanol. The authors show that ethanol suppresses the activation of astrocytes by inhibiting norepinephrine release which may contribute to the cognitive effects of alcohol intoxication.Liang YeMurat OrynbayevXiangyu ZhuEunice Y. LimRam R. DereddiAmit AgarwalDwight E. BerglesManzoor A. BhatMartin PaukertNature PortfolioarticleScienceQENNature Communications, Vol 11, Iss 1, Pp 1-20 (2020) |
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Science Q Liang Ye Murat Orynbayev Xiangyu Zhu Eunice Y. Lim Ram R. Dereddi Amit Agarwal Dwight E. Bergles Manzoor A. Bhat Martin Paukert Ethanol abolishes vigilance-dependent astroglia network activation in mice by inhibiting norepinephrine release |
description |
The effects of norepinephrine on sensory processing in cortical networks are altered by recreational drugs like ethanol. The authors show that ethanol suppresses the activation of astrocytes by inhibiting norepinephrine release which may contribute to the cognitive effects of alcohol intoxication. |
format |
article |
author |
Liang Ye Murat Orynbayev Xiangyu Zhu Eunice Y. Lim Ram R. Dereddi Amit Agarwal Dwight E. Bergles Manzoor A. Bhat Martin Paukert |
author_facet |
Liang Ye Murat Orynbayev Xiangyu Zhu Eunice Y. Lim Ram R. Dereddi Amit Agarwal Dwight E. Bergles Manzoor A. Bhat Martin Paukert |
author_sort |
Liang Ye |
title |
Ethanol abolishes vigilance-dependent astroglia network activation in mice by inhibiting norepinephrine release |
title_short |
Ethanol abolishes vigilance-dependent astroglia network activation in mice by inhibiting norepinephrine release |
title_full |
Ethanol abolishes vigilance-dependent astroglia network activation in mice by inhibiting norepinephrine release |
title_fullStr |
Ethanol abolishes vigilance-dependent astroglia network activation in mice by inhibiting norepinephrine release |
title_full_unstemmed |
Ethanol abolishes vigilance-dependent astroglia network activation in mice by inhibiting norepinephrine release |
title_sort |
ethanol abolishes vigilance-dependent astroglia network activation in mice by inhibiting norepinephrine release |
publisher |
Nature Portfolio |
publishDate |
2020 |
url |
https://doaj.org/article/2c1ad302fc1a4bc19e4ebac3ad4638f3 |
work_keys_str_mv |
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