Robust nucleation control via crisscross polymerization of highly coordinated DNA slats

For programmable DNA self-assembly, it is desirable to suppress spontaneous nucleation to enable all-or-nothing assembly of nanostructures far larger than a single DNA origami. Here the authors introduce crisscross polymerization of elongated slat monomers that engage beyond nearest neighbors, provi...

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Autores principales:	Dionis Minev, Christopher M. Wintersinger, Anastasia Ershova, William M. Shih
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2021
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/2c2609169ffc489a95495823973de4eb
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spelling	oai:doaj.org-article:2c2609169ffc489a95495823973de4eb2021-12-02T17:03:35ZRobust nucleation control via crisscross polymerization of highly coordinated DNA slats10.1038/s41467-021-21755-72041-1723https://doaj.org/article/2c2609169ffc489a95495823973de4eb2021-03-01T00:00:00Zhttps://doi.org/10.1038/s41467-021-21755-7https://doaj.org/toc/2041-1723For programmable DNA self-assembly, it is desirable to suppress spontaneous nucleation to enable all-or-nothing assembly of nanostructures far larger than a single DNA origami. Here the authors introduce crisscross polymerization of elongated slat monomers that engage beyond nearest neighbors, providing strictly seed-initiated nucleation of crisscross ribbons with distinct widths and twists.Dionis MinevChristopher M. WintersingerAnastasia ErshovaWilliam M. ShihNature PortfolioarticleScienceQENNature Communications, Vol 12, Iss 1, Pp 1-9 (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Dionis Minev Christopher M. Wintersinger Anastasia Ershova William M. Shih Robust nucleation control via crisscross polymerization of highly coordinated DNA slats
description	For programmable DNA self-assembly, it is desirable to suppress spontaneous nucleation to enable all-or-nothing assembly of nanostructures far larger than a single DNA origami. Here the authors introduce crisscross polymerization of elongated slat monomers that engage beyond nearest neighbors, providing strictly seed-initiated nucleation of crisscross ribbons with distinct widths and twists.
format	article
author	Dionis Minev Christopher M. Wintersinger Anastasia Ershova William M. Shih
author_facet	Dionis Minev Christopher M. Wintersinger Anastasia Ershova William M. Shih
author_sort	Dionis Minev
title	Robust nucleation control via crisscross polymerization of highly coordinated DNA slats
title_short	Robust nucleation control via crisscross polymerization of highly coordinated DNA slats
title_full	Robust nucleation control via crisscross polymerization of highly coordinated DNA slats
title_fullStr	Robust nucleation control via crisscross polymerization of highly coordinated DNA slats
title_full_unstemmed	Robust nucleation control via crisscross polymerization of highly coordinated DNA slats
title_sort	robust nucleation control via crisscross polymerization of highly coordinated dna slats
publisher	Nature Portfolio
publishDate	2021
url	https://doaj.org/article/2c2609169ffc489a95495823973de4eb
work_keys_str_mv	AT dionisminev robustnucleationcontrolviacrisscrosspolymerizationofhighlycoordinateddnaslats AT christophermwintersinger robustnucleationcontrolviacrisscrosspolymerizationofhighlycoordinateddnaslats AT anastasiaershova robustnucleationcontrolviacrisscrosspolymerizationofhighlycoordinateddnaslats AT williammshih robustnucleationcontrolviacrisscrosspolymerizationofhighlycoordinateddnaslats
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Robust nucleation control via crisscross polymerization of highly coordinated DNA slats

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