Variation in NOD2 augments Th2- and Th17 responses to myelin basic protein in multiple sclerosis.

Variation in NOD2 augments Th2- and Th17 responses to myelin basic protein in multiple sclerosis.

Variations in the gene for the nucleotide-binding oligomerisation domain (NOD) 2 have been associated with Crohn's disease but not multiple sclerosis (MS). Here we investigate the effect of three polymorphisms in the NOD2 gene (rs5743277, rs2066842 and rs5743291) on cytokine production and CD4+...

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Autores principales: Chris Juul Hedegaard, Christian Enevold, Finn Sellebjerg, Klaus Bendtzen, Claus Henrik Nielsen
Formato: article
Lenguaje:EN
Publicado: Public Library of Science (PLoS) 2011
Materias:
Medicine
R
Science
Q
Acceso en línea:https://doaj.org/article/2c36a59a22a64d47bd110bbaee8755ae
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