Assessment of utility values and QALYs after primary PCI with DP-Xience and BP-Biomatrix stents.

<h4>Background</h4>Primary percutaneous coronary intervention (PPCI) is the recommended treatment in ST elevated myocardial infarction (STEMI). The determination of Quality of life (QoL) for various options of coronary revascularization is important for establishment of a comprehensive c...

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Autores principales:	Salma Bibi, Amjad Khan, Asif Nadeem, Saima Mushtaq, Gul Majid Khan
Formato:	article
Lenguaje:	EN
Publicado:	Public Library of Science (PLoS) 2021
Materias:	Medicine R Science Q
Acceso en línea:	https://doaj.org/article/2c4122f7b3bb42e695fbfba0dc3bbd2f
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spelling	oai:doaj.org-article:2c4122f7b3bb42e695fbfba0dc3bbd2f2021-12-02T20:10:25ZAssessment of utility values and QALYs after primary PCI with DP-Xience and BP-Biomatrix stents.1932-620310.1371/journal.pone.0253290https://doaj.org/article/2c4122f7b3bb42e695fbfba0dc3bbd2f2021-01-01T00:00:00Zhttps://doi.org/10.1371/journal.pone.0253290https://doaj.org/toc/1932-6203<h4>Background</h4>Primary percutaneous coronary intervention (PPCI) is the recommended treatment in ST elevated myocardial infarction (STEMI). The determination of Quality of life (QoL) for various options of coronary revascularization is important for establishment of a comprehensive care plan. Studies of QoL in interventional cardiology are scarce. Our study has compared utility scores and quality adjusted life year (QALY) of 2nd and 3rd generation drug eluting stents (DES).<h4>Methods</h4>An observational cohort study was conducted to evaluate QoL and QALY using EQ-5D-5L questionnaire. Patients undergoing PPCI between July-Dec 2019 were evaluated after completion of one year of procedure.<h4>Results</h4>Total 334 patients were evaluated, study population consisted of a greater number of males (87.13%) than females. Mean utility value was more in 3rd G Biomatrix stents; 0.829 ± 0.11 than 2nd G Xience stents; 0.794 ± 0.11 (p < 0.05). Visual analogue scale (VAS) value was also high in 3rd G DES (81.84 ± 8.29) as compared to 2nd G DES (77.81 ± 9.01); p< 0.05. A significant association was found between utility scores/VAS and age, DM, HTN, Current smoking, family history and CAD diagnosis. There was a gain of 0.035 QALY with the use of Biomatrix DES.<h4>Conclusion</h4>Health related quality of life (HRQOL) is a leading support in the decision making of therapeutic interventions. Our study has found that Biodegradable polymer (BP) Biomatrix DES are superior to the Durable polymer (DP) Xience DES having better QoL and QALY.Salma BibiAmjad KhanAsif NadeemSaima MushtaqGul Majid KhanPublic Library of Science (PLoS)articleMedicineRScienceQENPLoS ONE, Vol 16, Iss 6, p e0253290 (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	Medicine R Science Q
spellingShingle	Medicine R Science Q Salma Bibi Amjad Khan Asif Nadeem Saima Mushtaq Gul Majid Khan Assessment of utility values and QALYs after primary PCI with DP-Xience and BP-Biomatrix stents.
description	<h4>Background</h4>Primary percutaneous coronary intervention (PPCI) is the recommended treatment in ST elevated myocardial infarction (STEMI). The determination of Quality of life (QoL) for various options of coronary revascularization is important for establishment of a comprehensive care plan. Studies of QoL in interventional cardiology are scarce. Our study has compared utility scores and quality adjusted life year (QALY) of 2nd and 3rd generation drug eluting stents (DES).<h4>Methods</h4>An observational cohort study was conducted to evaluate QoL and QALY using EQ-5D-5L questionnaire. Patients undergoing PPCI between July-Dec 2019 were evaluated after completion of one year of procedure.<h4>Results</h4>Total 334 patients were evaluated, study population consisted of a greater number of males (87.13%) than females. Mean utility value was more in 3rd G Biomatrix stents; 0.829 ± 0.11 than 2nd G Xience stents; 0.794 ± 0.11 (p < 0.05). Visual analogue scale (VAS) value was also high in 3rd G DES (81.84 ± 8.29) as compared to 2nd G DES (77.81 ± 9.01); p< 0.05. A significant association was found between utility scores/VAS and age, DM, HTN, Current smoking, family history and CAD diagnosis. There was a gain of 0.035 QALY with the use of Biomatrix DES.<h4>Conclusion</h4>Health related quality of life (HRQOL) is a leading support in the decision making of therapeutic interventions. Our study has found that Biodegradable polymer (BP) Biomatrix DES are superior to the Durable polymer (DP) Xience DES having better QoL and QALY.
format	article
author	Salma Bibi Amjad Khan Asif Nadeem Saima Mushtaq Gul Majid Khan
author_facet	Salma Bibi Amjad Khan Asif Nadeem Saima Mushtaq Gul Majid Khan
author_sort	Salma Bibi
title	Assessment of utility values and QALYs after primary PCI with DP-Xience and BP-Biomatrix stents.
title_short	Assessment of utility values and QALYs after primary PCI with DP-Xience and BP-Biomatrix stents.
title_full	Assessment of utility values and QALYs after primary PCI with DP-Xience and BP-Biomatrix stents.
title_fullStr	Assessment of utility values and QALYs after primary PCI with DP-Xience and BP-Biomatrix stents.
title_full_unstemmed	Assessment of utility values and QALYs after primary PCI with DP-Xience and BP-Biomatrix stents.
title_sort	assessment of utility values and qalys after primary pci with dp-xience and bp-biomatrix stents.
publisher	Public Library of Science (PLoS)
publishDate	2021
url	https://doaj.org/article/2c4122f7b3bb42e695fbfba0dc3bbd2f
work_keys_str_mv	AT salmabibi assessmentofutilityvaluesandqalysafterprimarypciwithdpxienceandbpbiomatrixstents AT amjadkhan assessmentofutilityvaluesandqalysafterprimarypciwithdpxienceandbpbiomatrixstents AT asifnadeem assessmentofutilityvaluesandqalysafterprimarypciwithdpxienceandbpbiomatrixstents AT saimamushtaq assessmentofutilityvaluesandqalysafterprimarypciwithdpxienceandbpbiomatrixstents AT gulmajidkhan assessmentofutilityvaluesandqalysafterprimarypciwithdpxienceandbpbiomatrixstents
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Assessment of utility values and QALYs after primary PCI with DP-Xience and BP-Biomatrix stents.

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