Magnetic nanoparticles for gene and drug delivery
Stuart C McBain, Humphrey HP Yiu, Jon DobsonInstitute of Science and Technology in Medicine, Keele University, Thornburrow Drive, Hartshill, Stoke-on-Trent, Staffordshire, ST4 7QB, U.K.Abstract: Investigations of magnetic micro- and nanoparticles for targeted drug delivery began over 30 years ago. S...
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Dove Medical Press
2008
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oai:doaj.org-article:2c444c41f2244292932236917e29afa22021-12-02T03:05:16ZMagnetic nanoparticles for gene and drug delivery1176-91141178-2013https://doaj.org/article/2c444c41f2244292932236917e29afa22008-06-01T00:00:00Zhttp://www.dovepress.com/magnetic-nanoparticles-for-gene-and-drug-delivery-a1838https://doaj.org/toc/1176-9114https://doaj.org/toc/1178-2013Stuart C McBain, Humphrey HP Yiu, Jon DobsonInstitute of Science and Technology in Medicine, Keele University, Thornburrow Drive, Hartshill, Stoke-on-Trent, Staffordshire, ST4 7QB, U.K.Abstract: Investigations of magnetic micro- and nanoparticles for targeted drug delivery began over 30 years ago. Since that time, major progress has been made in particle design and synthesis techniques, however, very few clinical trials have taken place. Here we review advances in magnetic nanoparticle design, in vitro and animal experiments with magnetic nanoparticle-based drug and gene delivery, and clinical trials of drug targeting.Keywords: magnetic nanoparticles, gene delivery, biotechnology Stuart C McBainHumphrey HP YiuJon DobsonDove Medical PressarticleMedicine (General)R5-920ENInternational Journal of Nanomedicine, Vol 2008, Iss Issue 2, Pp 169-180 (2008) |
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Medicine (General) R5-920 |
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Medicine (General) R5-920 Stuart C McBain Humphrey HP Yiu Jon Dobson Magnetic nanoparticles for gene and drug delivery |
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Stuart C McBain, Humphrey HP Yiu, Jon DobsonInstitute of Science and Technology in Medicine, Keele University, Thornburrow Drive, Hartshill, Stoke-on-Trent, Staffordshire, ST4 7QB, U.K.Abstract: Investigations of magnetic micro- and nanoparticles for targeted drug delivery began over 30 years ago. Since that time, major progress has been made in particle design and synthesis techniques, however, very few clinical trials have taken place. Here we review advances in magnetic nanoparticle design, in vitro and animal experiments with magnetic nanoparticle-based drug and gene delivery, and clinical trials of drug targeting.Keywords: magnetic nanoparticles, gene delivery, biotechnology |
format |
article |
author |
Stuart C McBain Humphrey HP Yiu Jon Dobson |
author_facet |
Stuart C McBain Humphrey HP Yiu Jon Dobson |
author_sort |
Stuart C McBain |
title |
Magnetic nanoparticles for gene and drug delivery |
title_short |
Magnetic nanoparticles for gene and drug delivery |
title_full |
Magnetic nanoparticles for gene and drug delivery |
title_fullStr |
Magnetic nanoparticles for gene and drug delivery |
title_full_unstemmed |
Magnetic nanoparticles for gene and drug delivery |
title_sort |
magnetic nanoparticles for gene and drug delivery |
publisher |
Dove Medical Press |
publishDate |
2008 |
url |
https://doaj.org/article/2c444c41f2244292932236917e29afa2 |
work_keys_str_mv |
AT stuartcmcbain magneticnanoparticlesforgeneanddrugdelivery AT humphreyhpyiu magneticnanoparticlesforgeneanddrugdelivery AT jondobson magneticnanoparticlesforgeneanddrugdelivery |
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1718401971562479616 |