PTPN22 gene and IL2RA rs11594656, rs2104286 gene variants: additional insights of polygenic single-nucleotide polymorphisms’ pattern among Egyptian children with type 1 diabetes

PTPN22 gene and IL2RA rs11594656, rs2104286 gene variants: additional insights of polygenic single-nucleotide polymorphisms’ pattern among Egyptian children with type 1 diabetes

Abstract Background Type 1 diabetes mellitus (T1D) results from environmental and genetic factors. We aimed to investigate the distribution of PTPN22, IL2RA rs11594656, and rs2104286 variants and its association with T1D in children. A case-control study conducted on 100 diabetic patients and 100 co...

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Autores principales: Soheir S. Abou El Ella, Maha A. Tawfik, Zeinab Sabri Mohammed, Naglaa Fathy Barseem
Formato: article
Lenguaje:EN
Publicado: SpringerOpen 2021
Materias:
PTPN22
IL2RA rs11594656
rs2104286
T1DM
And RFLP
Pediatrics
RJ1-570
Acceso en línea:https://doaj.org/article/2c48745f23de40f3880503e615cd7d40
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