Direct C–H difluoromethylation of heterocycles via organic photoredox catalysis

Heterocycles containing difluoromethyl groups are molecules with potential application in pharmaceutical, agricultural and materials science. Here, the authors show an organophotocatalytic difluoromethylation of heterocycles using O2 as green oxidant and preliminarily study the products’ bioactivity...

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Autores principales:	Wei Zhang, Xin-Xin Xiang, Junyi Chen, Chen Yang, Yu-Liang Pan, Jin-Pei Cheng, Qingbin Meng, Xin Li
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2020
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/2c4c4fd5844642eb90594faaeb6ca466
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spelling	oai:doaj.org-article:2c4c4fd5844642eb90594faaeb6ca4662021-12-02T15:37:11ZDirect C–H difluoromethylation of heterocycles via organic photoredox catalysis10.1038/s41467-020-14494-82041-1723https://doaj.org/article/2c4c4fd5844642eb90594faaeb6ca4662020-01-01T00:00:00Zhttps://doi.org/10.1038/s41467-020-14494-8https://doaj.org/toc/2041-1723Heterocycles containing difluoromethyl groups are molecules with potential application in pharmaceutical, agricultural and materials science. Here, the authors show an organophotocatalytic difluoromethylation of heterocycles using O2 as green oxidant and preliminarily study the products’ bioactivity.Wei ZhangXin-Xin XiangJunyi ChenChen YangYu-Liang PanJin-Pei ChengQingbin MengXin LiNature PortfolioarticleScienceQENNature Communications, Vol 11, Iss 1, Pp 1-10 (2020)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Wei Zhang Xin-Xin Xiang Junyi Chen Chen Yang Yu-Liang Pan Jin-Pei Cheng Qingbin Meng Xin Li Direct C–H difluoromethylation of heterocycles via organic photoredox catalysis
description	Heterocycles containing difluoromethyl groups are molecules with potential application in pharmaceutical, agricultural and materials science. Here, the authors show an organophotocatalytic difluoromethylation of heterocycles using O2 as green oxidant and preliminarily study the products’ bioactivity.
format	article
author	Wei Zhang Xin-Xin Xiang Junyi Chen Chen Yang Yu-Liang Pan Jin-Pei Cheng Qingbin Meng Xin Li
author_facet	Wei Zhang Xin-Xin Xiang Junyi Chen Chen Yang Yu-Liang Pan Jin-Pei Cheng Qingbin Meng Xin Li
author_sort	Wei Zhang
title	Direct C–H difluoromethylation of heterocycles via organic photoredox catalysis
title_short	Direct C–H difluoromethylation of heterocycles via organic photoredox catalysis
title_full	Direct C–H difluoromethylation of heterocycles via organic photoredox catalysis
title_fullStr	Direct C–H difluoromethylation of heterocycles via organic photoredox catalysis
title_full_unstemmed	Direct C–H difluoromethylation of heterocycles via organic photoredox catalysis
title_sort	direct c–h difluoromethylation of heterocycles via organic photoredox catalysis
publisher	Nature Portfolio
publishDate	2020
url	https://doaj.org/article/2c4c4fd5844642eb90594faaeb6ca466
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Direct C–H difluoromethylation of heterocycles via organic photoredox catalysis

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