Full-exon pyrosequencing screening of BRCA germline mutations in Mexican women with inherited breast and ovarian cancer.

Full-exon pyrosequencing screening of BRCA germline mutations in Mexican women with inherited breast and ovarian cancer.

Hereditary breast cancer comprises 10% of all breast cancers. The most prevalent genes causing this pathology are BRCA1 and BRCA2 (breast cancer early onset 1 and 2), which also predispose to other cancers. Despite the outstanding relevance of genetic screening of BRCA deleterious variants in patien...

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Detalles Bibliográficos
Autores principales: Felipe Vaca-Paniagua, Rosa María Alvarez-Gomez, Verónica Fragoso-Ontiveros, Silvia Vidal-Millan, Luis Alonso Herrera, David Cantú, Enrique Bargallo-Rocha, Alejandro Mohar, César López-Camarillo, Carlos Pérez-Plasencia
Formato: article
Lenguaje:EN
Publicado: Public Library of Science (PLoS) 2012
Materias:
Medicine
R
Science
Q
Acceso en línea:https://doaj.org/article/2c5d0369768842878eb1296cfc2a54a6
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