Schizophrenia, autism spectrum disorders and developmental disorders share specific disruptive coding mutations

Overlapping genes have been implicated in schizophrenia and neurodevelopmental disorders. Here, the authors overlap de novo variants in the two types of disorders and find variants in these genes with the same functional effect and in some cases the same specific variants.

Guardado en:
Detalles Bibliográficos
Autores principales: Elliott Rees, Hugo D. J. Creeth, Hai-Gwo Hwu, Wei J. Chen, Ming Tsuang, Stephen J. Glatt, Romain Rey, George Kirov, James T. R. Walters, Peter Holmans, Michael J. Owen, Michael C. O’Donovan
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2021
Materias:
Q
Acceso en línea:https://doaj.org/article/2c5e6d147085447d9cf1e2c12333d3cc
Etiquetas: Agregar Etiqueta
Sin Etiquetas, Sea el primero en etiquetar este registro!
Descripción
Sumario:Overlapping genes have been implicated in schizophrenia and neurodevelopmental disorders. Here, the authors overlap de novo variants in the two types of disorders and find variants in these genes with the same functional effect and in some cases the same specific variants.