Schizophrenia, autism spectrum disorders and developmental disorders share specific disruptive coding mutations

Overlapping genes have been implicated in schizophrenia and neurodevelopmental disorders. Here, the authors overlap de novo variants in the two types of disorders and find variants in these genes with the same functional effect and in some cases the same specific variants.

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Autores principales:	Elliott Rees, Hugo D. J. Creeth, Hai-Gwo Hwu, Wei J. Chen, Ming Tsuang, Stephen J. Glatt, Romain Rey, George Kirov, James T. R. Walters, Peter Holmans, Michael J. Owen, Michael C. O’Donovan
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2021
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/2c5e6d147085447d9cf1e2c12333d3cc
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spelling	oai:doaj.org-article:2c5e6d147085447d9cf1e2c12333d3cc2021-12-02T19:12:32ZSchizophrenia, autism spectrum disorders and developmental disorders share specific disruptive coding mutations10.1038/s41467-021-25532-42041-1723https://doaj.org/article/2c5e6d147085447d9cf1e2c12333d3cc2021-09-01T00:00:00Zhttps://doi.org/10.1038/s41467-021-25532-4https://doaj.org/toc/2041-1723Overlapping genes have been implicated in schizophrenia and neurodevelopmental disorders. Here, the authors overlap de novo variants in the two types of disorders and find variants in these genes with the same functional effect and in some cases the same specific variants.Elliott ReesHugo D. J. CreethHai-Gwo HwuWei J. ChenMing TsuangStephen J. GlattRomain ReyGeorge KirovJames T. R. WaltersPeter HolmansMichael J. OwenMichael C. O’DonovanNature PortfolioarticleScienceQENNature Communications, Vol 12, Iss 1, Pp 1-9 (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Elliott Rees Hugo D. J. Creeth Hai-Gwo Hwu Wei J. Chen Ming Tsuang Stephen J. Glatt Romain Rey George Kirov James T. R. Walters Peter Holmans Michael J. Owen Michael C. O’Donovan Schizophrenia, autism spectrum disorders and developmental disorders share specific disruptive coding mutations
description	Overlapping genes have been implicated in schizophrenia and neurodevelopmental disorders. Here, the authors overlap de novo variants in the two types of disorders and find variants in these genes with the same functional effect and in some cases the same specific variants.
format	article
author	Elliott Rees Hugo D. J. Creeth Hai-Gwo Hwu Wei J. Chen Ming Tsuang Stephen J. Glatt Romain Rey George Kirov James T. R. Walters Peter Holmans Michael J. Owen Michael C. O’Donovan
author_facet	Elliott Rees Hugo D. J. Creeth Hai-Gwo Hwu Wei J. Chen Ming Tsuang Stephen J. Glatt Romain Rey George Kirov James T. R. Walters Peter Holmans Michael J. Owen Michael C. O’Donovan
author_sort	Elliott Rees
title	Schizophrenia, autism spectrum disorders and developmental disorders share specific disruptive coding mutations
title_short	Schizophrenia, autism spectrum disorders and developmental disorders share specific disruptive coding mutations
title_full	Schizophrenia, autism spectrum disorders and developmental disorders share specific disruptive coding mutations
title_fullStr	Schizophrenia, autism spectrum disorders and developmental disorders share specific disruptive coding mutations
title_full_unstemmed	Schizophrenia, autism spectrum disorders and developmental disorders share specific disruptive coding mutations
title_sort	schizophrenia, autism spectrum disorders and developmental disorders share specific disruptive coding mutations
publisher	Nature Portfolio
publishDate	2021
url	https://doaj.org/article/2c5e6d147085447d9cf1e2c12333d3cc
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Schizophrenia, autism spectrum disorders and developmental disorders share specific disruptive coding mutations

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