Structural basis for amino acid transport by the CAT family of SLC7 transporters

Cationic amino acid transporters (CATs) belong to the physiologically important solute carrier (SLC) 7 family. Here, the authors present the structure of the mammalian CAT transporter homologue Geobacillus kaustophilus GkApcT, which reveals how arginine is recognized, and propose a model for proton-...

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Autores principales:	Katharina E. J. Jungnickel, Joanne L. Parker, Simon Newstead
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2018
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/2c65c0d0f0794387bf5392c87870ed24
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spelling	oai:doaj.org-article:2c65c0d0f0794387bf5392c87870ed242021-12-02T17:33:04ZStructural basis for amino acid transport by the CAT family of SLC7 transporters10.1038/s41467-018-03066-62041-1723https://doaj.org/article/2c65c0d0f0794387bf5392c87870ed242018-02-01T00:00:00Zhttps://doi.org/10.1038/s41467-018-03066-6https://doaj.org/toc/2041-1723Cationic amino acid transporters (CATs) belong to the physiologically important solute carrier (SLC) 7 family. Here, the authors present the structure of the mammalian CAT transporter homologue Geobacillus kaustophilus GkApcT, which reveals how arginine is recognized, and propose a model for proton-coupled amino acid transport.Katharina E. J. JungnickelJoanne L. ParkerSimon NewsteadNature PortfolioarticleScienceQENNature Communications, Vol 9, Iss 1, Pp 1-12 (2018)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Katharina E. J. Jungnickel Joanne L. Parker Simon Newstead Structural basis for amino acid transport by the CAT family of SLC7 transporters
description	Cationic amino acid transporters (CATs) belong to the physiologically important solute carrier (SLC) 7 family. Here, the authors present the structure of the mammalian CAT transporter homologue Geobacillus kaustophilus GkApcT, which reveals how arginine is recognized, and propose a model for proton-coupled amino acid transport.
format	article
author	Katharina E. J. Jungnickel Joanne L. Parker Simon Newstead
author_facet	Katharina E. J. Jungnickel Joanne L. Parker Simon Newstead
author_sort	Katharina E. J. Jungnickel
title	Structural basis for amino acid transport by the CAT family of SLC7 transporters
title_short	Structural basis for amino acid transport by the CAT family of SLC7 transporters
title_full	Structural basis for amino acid transport by the CAT family of SLC7 transporters
title_fullStr	Structural basis for amino acid transport by the CAT family of SLC7 transporters
title_full_unstemmed	Structural basis for amino acid transport by the CAT family of SLC7 transporters
title_sort	structural basis for amino acid transport by the cat family of slc7 transporters
publisher	Nature Portfolio
publishDate	2018
url	https://doaj.org/article/2c65c0d0f0794387bf5392c87870ed24
work_keys_str_mv	AT katharinaejjungnickel structuralbasisforaminoacidtransportbythecatfamilyofslc7transporters AT joannelparker structuralbasisforaminoacidtransportbythecatfamilyofslc7transporters AT simonnewstead structuralbasisforaminoacidtransportbythecatfamilyofslc7transporters
_version_	1718380053139554304

Structural basis for amino acid transport by the CAT family of SLC7 transporters

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