Structural basis for importin alpha 3 specificity of W proteins in Hendra and Nipah viruses

Importin α isoforms regulate the nuclear import of different cargo proteins but the mechanisms conferring isoform specificity are not fully understood. Here, the authors study the interactions of importin α1 and α3 with two viral cargos, elucidating the structural basis for isoform-specific cargo re...

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Auteurs principaux: Kate M. Smith, Sofiya Tsimbalyuk, Megan R. Edwards, Emily M. Cross, Jyoti Batra, Tatiana P. Soares da Costa, David Aragão, Christopher F. Basler, Jade K. Forwood
Format: article
Langue:EN
Publié: Nature Portfolio 2018
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Accès en ligne:https://doaj.org/article/2c7181d38279433e819e86bdf827aea6
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