A NEW APPROACH TO BRUCELLOSIS ALLERGODIAGNOSTICS

Abstract. The new cytometric method for laboratory diagnosis of brucellosis in vitro conditions based on detection of hypersensitivity to Brucella has been developed. This test allows to differentiate vaccinal and infectious processes in case of chronic brucellosis, and to measure the level of patie...

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Autores principales: D. G. Ponomarenko, O. V. Logvinenko, N. S. Sarkisian, C. L. Rakitinа, O. G. Golub, A. N. Kulichenko
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Lenguaje:RU
Publicado: Sankt-Peterburg : NIIÈM imeni Pastera 2014
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Acceso en línea:https://doaj.org/article/2c763300576f4907b259bfcf788f4ddd
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spelling oai:doaj.org-article:2c763300576f4907b259bfcf788f4ddd2021-11-22T07:09:46ZA NEW APPROACH TO BRUCELLOSIS ALLERGODIAGNOSTICS2220-76192313-739810.15789/2220-7619-2013-1-89-92https://doaj.org/article/2c763300576f4907b259bfcf788f4ddd2014-07-01T00:00:00Zhttps://www.iimmun.ru/iimm/article/view/134https://doaj.org/toc/2220-7619https://doaj.org/toc/2313-7398Abstract. The new cytometric method for laboratory diagnosis of brucellosis in vitro conditions based on detection of hypersensitivity to Brucella has been developed. This test allows to differentiate vaccinal and infectious processes in case of chronic brucellosis, and to measure the level of patient sensibilization to Brucella. Thus, the test might be used to estimate intensity of post-vaccination immunity before re-immunization against brucellosis. Using of flow cytometry in the test excludes additional antigenic influence on human organism and allows to provide testing within 1 hour.D. G. PonomarenkoO. V. LogvinenkoN. S. SarkisianC. L. RakitinаO. G. GolubA. N. KulichenkoSankt-Peterburg : NIIÈM imeni Pasteraarticlebrucellosisallergic diagnosticsflow cytometryInfectious and parasitic diseasesRC109-216RUInfekciâ i Immunitet, Vol 3, Iss 1, Pp 89-92 (2014)
institution DOAJ
collection DOAJ
language RU
topic brucellosis
allergic diagnostics
flow cytometry
Infectious and parasitic diseases
RC109-216
spellingShingle brucellosis
allergic diagnostics
flow cytometry
Infectious and parasitic diseases
RC109-216
D. G. Ponomarenko
O. V. Logvinenko
N. S. Sarkisian
C. L. Rakitinа
O. G. Golub
A. N. Kulichenko
A NEW APPROACH TO BRUCELLOSIS ALLERGODIAGNOSTICS
description Abstract. The new cytometric method for laboratory diagnosis of brucellosis in vitro conditions based on detection of hypersensitivity to Brucella has been developed. This test allows to differentiate vaccinal and infectious processes in case of chronic brucellosis, and to measure the level of patient sensibilization to Brucella. Thus, the test might be used to estimate intensity of post-vaccination immunity before re-immunization against brucellosis. Using of flow cytometry in the test excludes additional antigenic influence on human organism and allows to provide testing within 1 hour.
format article
author D. G. Ponomarenko
O. V. Logvinenko
N. S. Sarkisian
C. L. Rakitinа
O. G. Golub
A. N. Kulichenko
author_facet D. G. Ponomarenko
O. V. Logvinenko
N. S. Sarkisian
C. L. Rakitinа
O. G. Golub
A. N. Kulichenko
author_sort D. G. Ponomarenko
title A NEW APPROACH TO BRUCELLOSIS ALLERGODIAGNOSTICS
title_short A NEW APPROACH TO BRUCELLOSIS ALLERGODIAGNOSTICS
title_full A NEW APPROACH TO BRUCELLOSIS ALLERGODIAGNOSTICS
title_fullStr A NEW APPROACH TO BRUCELLOSIS ALLERGODIAGNOSTICS
title_full_unstemmed A NEW APPROACH TO BRUCELLOSIS ALLERGODIAGNOSTICS
title_sort new approach to brucellosis allergodiagnostics
publisher Sankt-Peterburg : NIIÈM imeni Pastera
publishDate 2014
url https://doaj.org/article/2c763300576f4907b259bfcf788f4ddd
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