Cytomegalovirus Cholangiopathy in an Immunocompetent Patient: A Case Report and Literature Review

A 37-year-old man presented with jaundice, upper right quadrant pain, and intermittent fever with chills. Laboratory assessment showed biliary stasis, with total bilirubin of 203 µmol/L (2–20), conjugated bilirubin of 105 µmol/L, and alkaline phosphatase of 556 U/L (30–120). Markers for hepatitis A–...

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Autores principales:	Ervin Alibegovic, Admir Kurtcehajic, Boris Ilic, Ahmed Hujdurovic, Edinka Smajic, Amar Habibovic, Darja Perkunic
Formato:	article
Lenguaje:	EN
Publicado:	Hindawi Limited 2021
Materias:	Diseases of the digestive system. Gastroenterology RC799-869
Acceso en línea:	https://doaj.org/article/2c77b59df6984280ab7dfebe15b0639b
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spelling	oai:doaj.org-article:2c77b59df6984280ab7dfebe15b0639b2021-11-22T01:09:46ZCytomegalovirus Cholangiopathy in an Immunocompetent Patient: A Case Report and Literature Review2090-659510.1155/2021/2420668https://doaj.org/article/2c77b59df6984280ab7dfebe15b0639b2021-01-01T00:00:00Zhttp://dx.doi.org/10.1155/2021/2420668https://doaj.org/toc/2090-6595A 37-year-old man presented with jaundice, upper right quadrant pain, and intermittent fever with chills. Laboratory assessment showed biliary stasis, with total bilirubin of 203 µmol/L (2–20), conjugated bilirubin of 105 µmol/L, and alkaline phosphatase of 556 U/L (30–120). Markers for hepatitis A–E viruses were negative. Serology assessment for rubeola, herpes simplex virus, Epstein-Barr virus, and Toxoplasma gondii showed negative IgM antibodies. HIV serology status was negative. For cytomegalovirus, both types of antibodies (IgM and IgG) were positive, with an IgM level >300 U/mL. pp65 antigen was also detected as well as CMV DNA. Diagnostic imaging of the abdomen except the dilated common bile duct showed a normal appearance of the gallbladder, liver, pancreas, spleen, and both kidneys. To our knowledge, cytomegalovirus cholangiopathy in the absence of any other underlying disease has not been reported. Therefore, the presence of cholangiopathy in our patient is interesting from an imaging, laboratory, and clinical point of view.Ervin AlibegovicAdmir KurtcehajicBoris IlicAhmed HujdurovicEdinka SmajicAmar HabibovicDarja PerkunicHindawi LimitedarticleDiseases of the digestive system. GastroenterologyRC799-869ENCase Reports in Hepatology, Vol 2021 (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	Diseases of the digestive system. Gastroenterology RC799-869
spellingShingle	Diseases of the digestive system. Gastroenterology RC799-869 Ervin Alibegovic Admir Kurtcehajic Boris Ilic Ahmed Hujdurovic Edinka Smajic Amar Habibovic Darja Perkunic Cytomegalovirus Cholangiopathy in an Immunocompetent Patient: A Case Report and Literature Review
description	A 37-year-old man presented with jaundice, upper right quadrant pain, and intermittent fever with chills. Laboratory assessment showed biliary stasis, with total bilirubin of 203 µmol/L (2–20), conjugated bilirubin of 105 µmol/L, and alkaline phosphatase of 556 U/L (30–120). Markers for hepatitis A–E viruses were negative. Serology assessment for rubeola, herpes simplex virus, Epstein-Barr virus, and Toxoplasma gondii showed negative IgM antibodies. HIV serology status was negative. For cytomegalovirus, both types of antibodies (IgM and IgG) were positive, with an IgM level >300 U/mL. pp65 antigen was also detected as well as CMV DNA. Diagnostic imaging of the abdomen except the dilated common bile duct showed a normal appearance of the gallbladder, liver, pancreas, spleen, and both kidneys. To our knowledge, cytomegalovirus cholangiopathy in the absence of any other underlying disease has not been reported. Therefore, the presence of cholangiopathy in our patient is interesting from an imaging, laboratory, and clinical point of view.
format	article
author	Ervin Alibegovic Admir Kurtcehajic Boris Ilic Ahmed Hujdurovic Edinka Smajic Amar Habibovic Darja Perkunic
author_facet	Ervin Alibegovic Admir Kurtcehajic Boris Ilic Ahmed Hujdurovic Edinka Smajic Amar Habibovic Darja Perkunic
author_sort	Ervin Alibegovic
title	Cytomegalovirus Cholangiopathy in an Immunocompetent Patient: A Case Report and Literature Review
title_short	Cytomegalovirus Cholangiopathy in an Immunocompetent Patient: A Case Report and Literature Review
title_full	Cytomegalovirus Cholangiopathy in an Immunocompetent Patient: A Case Report and Literature Review
title_fullStr	Cytomegalovirus Cholangiopathy in an Immunocompetent Patient: A Case Report and Literature Review
title_full_unstemmed	Cytomegalovirus Cholangiopathy in an Immunocompetent Patient: A Case Report and Literature Review
title_sort	cytomegalovirus cholangiopathy in an immunocompetent patient: a case report and literature review
publisher	Hindawi Limited
publishDate	2021
url	https://doaj.org/article/2c77b59df6984280ab7dfebe15b0639b
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Cytomegalovirus Cholangiopathy in an Immunocompetent Patient: A Case Report and Literature Review

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