The relationship between the characteristics of burst suppression pattern and different etiologies in epilepsy

Abstract To analyze the relationship between the characteristics of burst suppression (BS) pattern and different etiologies in epilepsy. Patients with a BS pattern who were younger than 6 months old were screened from our electroencephalogram (EEG) database. The synchronized and symmetric BS pattern...

Descripción completa

Guardado en:

Detalles Bibliográficos
Autores principales:	Haipo Yang, Pan Gong, Xianru Jiao, Qiujun Zhou, Yuehua Zhang, Yuwu Jiang, Zhixian Yang
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2021
Materias:	Medicine R Science Q
Acceso en línea:	https://doaj.org/article/2c7984dbc3004d6ab72a4d2f9004d50e
Etiquetas:	Agregar Etiqueta Sin Etiquetas, Sea el primero en etiquetar este registro!

id	oai:doaj.org-article:2c7984dbc3004d6ab72a4d2f9004d50e
record_format	dspace
spelling	oai:doaj.org-article:2c7984dbc3004d6ab72a4d2f9004d50e2021-12-02T16:35:42ZThe relationship between the characteristics of burst suppression pattern and different etiologies in epilepsy10.1038/s41598-021-95040-42045-2322https://doaj.org/article/2c7984dbc3004d6ab72a4d2f9004d50e2021-08-01T00:00:00Zhttps://doi.org/10.1038/s41598-021-95040-4https://doaj.org/toc/2045-2322Abstract To analyze the relationship between the characteristics of burst suppression (BS) pattern and different etiologies in epilepsy. Patients with a BS pattern who were younger than 6 months old were screened from our electroencephalogram (EEG) database. The synchronized and symmetric BS patterns under different etiologies in epilepsy were analyzed. A total of 32 patients had a BS pattern on EEG. The etiologies included genetic disorders (37.5%), cortical malformations (28.1%), inborn errors of metabolism (12.5%), and unknown (21.9%). Twenty-five patients were diagnosed with Ohtahara syndrome, one as early myoclonic encephalopathy, and one as epilepsy of infancy with migrating focal seizure. Five cases could not be classified into any epileptic syndrome. Asynchronous BS pattern was identified in 18 cases, of which 13 (72%) patients had genetic and/or metabolic etiologies. Synchronous BS pattern was identified in 14 cases, of which 8 (57%) patients had structural etiologies. Twenty-three patients had symmetric BS patterns, of which 15 (65%) patients had genetic etiologies. Nine patients had asymmetric BS patterns, of which 8 (89%) patients had structural etiologies. Patients with genetic epilepsies tended to have asynchronous and symmetric BS patterns, whereas those with structural epilepsies were more likely to have synchronous and asymmetric BS patterns.Haipo YangPan GongXianru JiaoQiujun ZhouYuehua ZhangYuwu JiangZhixian YangNature PortfolioarticleMedicineRScienceQENScientific Reports, Vol 11, Iss 1, Pp 1-8 (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	Medicine R Science Q
spellingShingle	Medicine R Science Q Haipo Yang Pan Gong Xianru Jiao Qiujun Zhou Yuehua Zhang Yuwu Jiang Zhixian Yang The relationship between the characteristics of burst suppression pattern and different etiologies in epilepsy
description	Abstract To analyze the relationship between the characteristics of burst suppression (BS) pattern and different etiologies in epilepsy. Patients with a BS pattern who were younger than 6 months old were screened from our electroencephalogram (EEG) database. The synchronized and symmetric BS patterns under different etiologies in epilepsy were analyzed. A total of 32 patients had a BS pattern on EEG. The etiologies included genetic disorders (37.5%), cortical malformations (28.1%), inborn errors of metabolism (12.5%), and unknown (21.9%). Twenty-five patients were diagnosed with Ohtahara syndrome, one as early myoclonic encephalopathy, and one as epilepsy of infancy with migrating focal seizure. Five cases could not be classified into any epileptic syndrome. Asynchronous BS pattern was identified in 18 cases, of which 13 (72%) patients had genetic and/or metabolic etiologies. Synchronous BS pattern was identified in 14 cases, of which 8 (57%) patients had structural etiologies. Twenty-three patients had symmetric BS patterns, of which 15 (65%) patients had genetic etiologies. Nine patients had asymmetric BS patterns, of which 8 (89%) patients had structural etiologies. Patients with genetic epilepsies tended to have asynchronous and symmetric BS patterns, whereas those with structural epilepsies were more likely to have synchronous and asymmetric BS patterns.
format	article
author	Haipo Yang Pan Gong Xianru Jiao Qiujun Zhou Yuehua Zhang Yuwu Jiang Zhixian Yang
author_facet	Haipo Yang Pan Gong Xianru Jiao Qiujun Zhou Yuehua Zhang Yuwu Jiang Zhixian Yang
author_sort	Haipo Yang
title	The relationship between the characteristics of burst suppression pattern and different etiologies in epilepsy
title_short	The relationship between the characteristics of burst suppression pattern and different etiologies in epilepsy
title_full	The relationship between the characteristics of burst suppression pattern and different etiologies in epilepsy
title_fullStr	The relationship between the characteristics of burst suppression pattern and different etiologies in epilepsy
title_full_unstemmed	The relationship between the characteristics of burst suppression pattern and different etiologies in epilepsy
title_sort	relationship between the characteristics of burst suppression pattern and different etiologies in epilepsy
publisher	Nature Portfolio
publishDate	2021
url	https://doaj.org/article/2c7984dbc3004d6ab72a4d2f9004d50e
work_keys_str_mv	AT haipoyang therelationshipbetweenthecharacteristicsofburstsuppressionpatternanddifferentetiologiesinepilepsy AT pangong therelationshipbetweenthecharacteristicsofburstsuppressionpatternanddifferentetiologiesinepilepsy AT xianrujiao therelationshipbetweenthecharacteristicsofburstsuppressionpatternanddifferentetiologiesinepilepsy AT qiujunzhou therelationshipbetweenthecharacteristicsofburstsuppressionpatternanddifferentetiologiesinepilepsy AT yuehuazhang therelationshipbetweenthecharacteristicsofburstsuppressionpatternanddifferentetiologiesinepilepsy AT yuwujiang therelationshipbetweenthecharacteristicsofburstsuppressionpatternanddifferentetiologiesinepilepsy AT zhixianyang therelationshipbetweenthecharacteristicsofburstsuppressionpatternanddifferentetiologiesinepilepsy AT haipoyang relationshipbetweenthecharacteristicsofburstsuppressionpatternanddifferentetiologiesinepilepsy AT pangong relationshipbetweenthecharacteristicsofburstsuppressionpatternanddifferentetiologiesinepilepsy AT xianrujiao relationshipbetweenthecharacteristicsofburstsuppressionpatternanddifferentetiologiesinepilepsy AT qiujunzhou relationshipbetweenthecharacteristicsofburstsuppressionpatternanddifferentetiologiesinepilepsy AT yuehuazhang relationshipbetweenthecharacteristicsofburstsuppressionpatternanddifferentetiologiesinepilepsy AT yuwujiang relationshipbetweenthecharacteristicsofburstsuppressionpatternanddifferentetiologiesinepilepsy AT zhixianyang relationshipbetweenthecharacteristicsofburstsuppressionpatternanddifferentetiologiesinepilepsy
_version_	1718383682401599488

The relationship between the characteristics of burst suppression pattern and different etiologies in epilepsy

Ejemplares similares