Tumor Marker B7-H6 Bound to the Coiled Coil Peptide-Polymer Conjugate Enables Targeted Therapy by Activating Human Natural Killer Cells

Targeted cancer immunotherapy is a promising tool for restoring immune surveillance and eradicating cancer cells. Hydrophilic polymers modified with coiled coil peptide tags can be used as universal carriers designed for cell-specific delivery of such biologically active proteins. Here, we describe...

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Main Authors: Barbora Kalousková, Ondřej Skořepa, Denis Cmunt, Celeste Abreu, Kateřina Krejčová, Jan Bláha, Irena Sieglová, Vlastimil Král, Milan Fábry, Robert Pola, Michal Pechar, Ondřej Vaněk
Format: article
Language:EN
Published: MDPI AG 2021
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Online Access:https://doaj.org/article/2c9043d3a1e7484f806ef4bdcff6e30e
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