Detection of clinically silent brain lesions in [18F]FDG PET/CT study in oncological patients: analysis of over 10,000 studies

Abstract The study aimed to show that including the brain region into the standard 2-deoxy-2-[18F]fluoro-d-glucose positron emission tomography/computed tomography ([18F]FDG PET/CT) study protocol may result in detecting clinically silent brain tumours. We retrospectively analyzed the group of 10,37...

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Autores principales:	Agata Pietrzak, Andrzej Marszałek, Jolanta Kunikowska, Tomasz Piotrowski, Adrianna Medak, Katarzyna Pietrasz, Julia Wojtowicz, Witold Cholewiński
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2021
Materias:	Medicine R Science Q
Acceso en línea:	https://doaj.org/article/2c90b01a7b6944f99416168cbcb39c54
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spelling	oai:doaj.org-article:2c90b01a7b6944f99416168cbcb39c542021-12-02T17:24:02ZDetection of clinically silent brain lesions in [18F]FDG PET/CT study in oncological patients: analysis of over 10,000 studies10.1038/s41598-021-98004-w2045-2322https://doaj.org/article/2c90b01a7b6944f99416168cbcb39c542021-09-01T00:00:00Zhttps://doi.org/10.1038/s41598-021-98004-whttps://doaj.org/toc/2045-2322Abstract The study aimed to show that including the brain region into the standard 2-deoxy-2-[18F]fluoro-d-glucose positron emission tomography/computed tomography ([18F]FDG PET/CT) study protocol may result in detecting clinically silent brain tumours. We retrospectively analyzed the group of 10,378 from the total of 12,011 consecutive patients who underwent the torso and brain [18F]FDG PET/CT scanning, considering an ability of the method to evaluate undetected before brain tumours in patients diagnosed and treated in our institution. While collecting the database, we followed the inclusion criteria: at least 1-year of follow-up, a full medical history collected in our institution, histopathologic examination or other studies available to confirm the type of observed lesion, and the most importantly—no brain lesions reported in the patients’ medical data. In this study, performing the torso and brain [18F]FDG PET/CT imaging helped to detect clinically silent primary and metastatic brain tumours in 129 patients, and the benign lesions in 24 studied cases, in whom no suspicious brain findings were reported prior to the examination. In conclusion, including the brain region into the standard [18F]FDG PET/CT protocol can be considered helpful in detecting clinically silent malignant and benign brain tumours.Agata PietrzakAndrzej MarszałekJolanta KunikowskaTomasz PiotrowskiAdrianna MedakKatarzyna PietraszJulia WojtowiczWitold CholewińskiNature PortfolioarticleMedicineRScienceQENScientific Reports, Vol 11, Iss 1, Pp 1-7 (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	Medicine R Science Q
spellingShingle	Medicine R Science Q Agata Pietrzak Andrzej Marszałek Jolanta Kunikowska Tomasz Piotrowski Adrianna Medak Katarzyna Pietrasz Julia Wojtowicz Witold Cholewiński Detection of clinically silent brain lesions in [18F]FDG PET/CT study in oncological patients: analysis of over 10,000 studies
description	Abstract The study aimed to show that including the brain region into the standard 2-deoxy-2-[18F]fluoro-d-glucose positron emission tomography/computed tomography ([18F]FDG PET/CT) study protocol may result in detecting clinically silent brain tumours. We retrospectively analyzed the group of 10,378 from the total of 12,011 consecutive patients who underwent the torso and brain [18F]FDG PET/CT scanning, considering an ability of the method to evaluate undetected before brain tumours in patients diagnosed and treated in our institution. While collecting the database, we followed the inclusion criteria: at least 1-year of follow-up, a full medical history collected in our institution, histopathologic examination or other studies available to confirm the type of observed lesion, and the most importantly—no brain lesions reported in the patients’ medical data. In this study, performing the torso and brain [18F]FDG PET/CT imaging helped to detect clinically silent primary and metastatic brain tumours in 129 patients, and the benign lesions in 24 studied cases, in whom no suspicious brain findings were reported prior to the examination. In conclusion, including the brain region into the standard [18F]FDG PET/CT protocol can be considered helpful in detecting clinically silent malignant and benign brain tumours.
format	article
author	Agata Pietrzak Andrzej Marszałek Jolanta Kunikowska Tomasz Piotrowski Adrianna Medak Katarzyna Pietrasz Julia Wojtowicz Witold Cholewiński
author_facet	Agata Pietrzak Andrzej Marszałek Jolanta Kunikowska Tomasz Piotrowski Adrianna Medak Katarzyna Pietrasz Julia Wojtowicz Witold Cholewiński
author_sort	Agata Pietrzak
title	Detection of clinically silent brain lesions in [18F]FDG PET/CT study in oncological patients: analysis of over 10,000 studies
title_short	Detection of clinically silent brain lesions in [18F]FDG PET/CT study in oncological patients: analysis of over 10,000 studies
title_full	Detection of clinically silent brain lesions in [18F]FDG PET/CT study in oncological patients: analysis of over 10,000 studies
title_fullStr	Detection of clinically silent brain lesions in [18F]FDG PET/CT study in oncological patients: analysis of over 10,000 studies
title_full_unstemmed	Detection of clinically silent brain lesions in [18F]FDG PET/CT study in oncological patients: analysis of over 10,000 studies
title_sort	detection of clinically silent brain lesions in [18f]fdg pet/ct study in oncological patients: analysis of over 10,000 studies
publisher	Nature Portfolio
publishDate	2021
url	https://doaj.org/article/2c90b01a7b6944f99416168cbcb39c54
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Detection of clinically silent brain lesions in [18F]FDG PET/CT study in oncological patients: analysis of over 10,000 studies

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