Hepatic saturated fatty acid fraction is associated with de novo lipogenesis and hepatic insulin resistance

Hepatic steatosis is associated with poor cardiometabolic health, with de novo lipogenesis (DNL) contributing to hepatic steatosis and subsequent insulin resistance. Here, the authors use 1H-MRS methodology to show hepatic SFA fraction is a measure of DNL and specifically may hamper hepatic insulin...

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Auteurs principaux: Kay H. M. Roumans, Lucas Lindeboom, Pandichelvam Veeraiah, Carlijn M. E. Remie, Esther Phielix, Bas Havekes, Yvonne M. H. Bruls, Martijn C. G. J. Brouwers, Marcus Ståhlman, Marjan Alssema, Harry P. F. Peters, Renée de Mutsert, Bart Staels, Marja-Riitta Taskinen, Jan Borén, Patrick Schrauwen, Vera B. Schrauwen-Hinderling
Format: article
Langue:EN
Publié: Nature Portfolio 2020
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Accès en ligne:https://doaj.org/article/2c9a2f8b1cf44a76b5b73a890bc8f73e
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