Clinical Features and Outcomes of Patients with Chemotherapy-induced Takotsubo Syndrome

Chemotherapy treatment of malignancy accounts for 1–2% of takotsubo syndrome (TS) triggers. Women comprise 60–70% of patients with chemotherapy-associated TS, a distinctly lower prevalence than the 90% female prevalence in TS overall. Fluorouracil is the most commonly reported TS-triggering chemothe...

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Autores principales: Katelyn Storey, Scott W Sharkey
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Lenguaje:EN
Publicado: Radcliffe Medical Media 2020
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Acceso en línea:https://doaj.org/article/2ca97b83a2134bdabf38af4fc13a2ed4
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spelling oai:doaj.org-article:2ca97b83a2134bdabf38af4fc13a2ed42021-12-04T16:02:18ZClinical Features and Outcomes of Patients with Chemotherapy-induced Takotsubo Syndrome10.15420/usc.2019.10.11758-390X1758-3896https://doaj.org/article/2ca97b83a2134bdabf38af4fc13a2ed42020-02-01T00:00:00Zhttps://www.uscjournal.com/articles/Chemotherapy-Induced-Takotsubo-Syndromehttps://doaj.org/toc/1758-3896https://doaj.org/toc/1758-390XChemotherapy treatment of malignancy accounts for 1–2% of takotsubo syndrome (TS) triggers. Women comprise 60–70% of patients with chemotherapy-associated TS, a distinctly lower prevalence than the 90% female prevalence in TS overall. Fluorouracil is the most commonly reported TS-triggering chemotherapeutic agent, although this must be interpreted in the context of the frequency of worldwide use of this agent. The onset of TS relative to chemotherapy initiation is quite variable, ranging from the initial administration to subsequent chemotherapy cycles several weeks beyond initiation. Limited information suggests chemotherapy can be safely reinitiated once the patient has recovered from the initial TS event. Having a TS event in the setting of chemotherapy treatment for malignancy is associated with substantial mortality.Katelyn StoreyScott W SharkeyRadcliffe Medical MediaarticleDiseases of the circulatory (Cardiovascular) systemRC666-701ENUS Cardiology Review , Vol 13, Iss 2, Pp 74-82 (2020)
institution DOAJ
collection DOAJ
language EN
topic Diseases of the circulatory (Cardiovascular) system
RC666-701
spellingShingle Diseases of the circulatory (Cardiovascular) system
RC666-701
Katelyn Storey
Scott W Sharkey
Clinical Features and Outcomes of Patients with Chemotherapy-induced Takotsubo Syndrome
description Chemotherapy treatment of malignancy accounts for 1–2% of takotsubo syndrome (TS) triggers. Women comprise 60–70% of patients with chemotherapy-associated TS, a distinctly lower prevalence than the 90% female prevalence in TS overall. Fluorouracil is the most commonly reported TS-triggering chemotherapeutic agent, although this must be interpreted in the context of the frequency of worldwide use of this agent. The onset of TS relative to chemotherapy initiation is quite variable, ranging from the initial administration to subsequent chemotherapy cycles several weeks beyond initiation. Limited information suggests chemotherapy can be safely reinitiated once the patient has recovered from the initial TS event. Having a TS event in the setting of chemotherapy treatment for malignancy is associated with substantial mortality.
format article
author Katelyn Storey
Scott W Sharkey
author_facet Katelyn Storey
Scott W Sharkey
author_sort Katelyn Storey
title Clinical Features and Outcomes of Patients with Chemotherapy-induced Takotsubo Syndrome
title_short Clinical Features and Outcomes of Patients with Chemotherapy-induced Takotsubo Syndrome
title_full Clinical Features and Outcomes of Patients with Chemotherapy-induced Takotsubo Syndrome
title_fullStr Clinical Features and Outcomes of Patients with Chemotherapy-induced Takotsubo Syndrome
title_full_unstemmed Clinical Features and Outcomes of Patients with Chemotherapy-induced Takotsubo Syndrome
title_sort clinical features and outcomes of patients with chemotherapy-induced takotsubo syndrome
publisher Radcliffe Medical Media
publishDate 2020
url https://doaj.org/article/2ca97b83a2134bdabf38af4fc13a2ed4
work_keys_str_mv AT katelynstorey clinicalfeaturesandoutcomesofpatientswithchemotherapyinducedtakotsubosyndrome
AT scottwsharkey clinicalfeaturesandoutcomesofpatientswithchemotherapyinducedtakotsubosyndrome
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