HSV Esophagitis in an Immunocompetent 17-Year-Old

Herpes Simplex Virus (HSV) esophagitis is a relatively rare form of infectious esophagitis. Typically, patients with viral esophagitis are immunocompromised. HSV esophagitis in an immunocompetent patient is uncommonly reported. The objective of this case report is to discuss symptoms, investigations...

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Autores principales: Vedika Rajasekaran BS, Victoria Rahaman MD, Xing Hou MD, Russell W. Steele MD
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Lenguaje:EN
Publicado: SAGE Publishing 2021
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Acceso en línea:https://doaj.org/article/2cb6d24c869f46b7a6efe55fc083ec5a
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spelling oai:doaj.org-article:2cb6d24c869f46b7a6efe55fc083ec5a2021-11-23T23:04:02ZHSV Esophagitis in an Immunocompetent 17-Year-Old2333-794X10.1177/2333794X211052914https://doaj.org/article/2cb6d24c869f46b7a6efe55fc083ec5a2021-11-01T00:00:00Zhttps://doi.org/10.1177/2333794X211052914https://doaj.org/toc/2333-794XHerpes Simplex Virus (HSV) esophagitis is a relatively rare form of infectious esophagitis. Typically, patients with viral esophagitis are immunocompromised. HSV esophagitis in an immunocompetent patient is uncommonly reported. The objective of this case report is to discuss symptoms, investigations, imaging, and treatment of HSV esophagitis in a healthy adolescent male. A previously healthy 17-year-old male presented to the ED of our facility with a 5-day history of fever, odynophagia, lethargy, and 2 episodes of emesis that failed to resolve with antibiotic treatment. Investigations revealed a low platelet count, mild hyponatremia, hypochloremia, and an elevated AST and ALT. A respiratory infection panel as well as CMV IgG, HIV, Rickettsia, and EBV tests were negative. HSV-1 PCR was positive and upper endoscopy revealed a friable mucosa, erythema, and exudates in the lower esophagus and erythematous duodenopathy. The patient received a diagnosis of HSV esophagitis and was treated with a 14-day course of IV to PO acyclovir. There was a rapid improvement of his symptoms with antiviral therapy.Vedika Rajasekaran BSVictoria Rahaman MDXing Hou MDRussell W. Steele MDSAGE PublishingarticlePediatricsRJ1-570ENGlobal Pediatric Health, Vol 8 (2021)
institution DOAJ
collection DOAJ
language EN
topic Pediatrics
RJ1-570
spellingShingle Pediatrics
RJ1-570
Vedika Rajasekaran BS
Victoria Rahaman MD
Xing Hou MD
Russell W. Steele MD
HSV Esophagitis in an Immunocompetent 17-Year-Old
description Herpes Simplex Virus (HSV) esophagitis is a relatively rare form of infectious esophagitis. Typically, patients with viral esophagitis are immunocompromised. HSV esophagitis in an immunocompetent patient is uncommonly reported. The objective of this case report is to discuss symptoms, investigations, imaging, and treatment of HSV esophagitis in a healthy adolescent male. A previously healthy 17-year-old male presented to the ED of our facility with a 5-day history of fever, odynophagia, lethargy, and 2 episodes of emesis that failed to resolve with antibiotic treatment. Investigations revealed a low platelet count, mild hyponatremia, hypochloremia, and an elevated AST and ALT. A respiratory infection panel as well as CMV IgG, HIV, Rickettsia, and EBV tests were negative. HSV-1 PCR was positive and upper endoscopy revealed a friable mucosa, erythema, and exudates in the lower esophagus and erythematous duodenopathy. The patient received a diagnosis of HSV esophagitis and was treated with a 14-day course of IV to PO acyclovir. There was a rapid improvement of his symptoms with antiviral therapy.
format article
author Vedika Rajasekaran BS
Victoria Rahaman MD
Xing Hou MD
Russell W. Steele MD
author_facet Vedika Rajasekaran BS
Victoria Rahaman MD
Xing Hou MD
Russell W. Steele MD
author_sort Vedika Rajasekaran BS
title HSV Esophagitis in an Immunocompetent 17-Year-Old
title_short HSV Esophagitis in an Immunocompetent 17-Year-Old
title_full HSV Esophagitis in an Immunocompetent 17-Year-Old
title_fullStr HSV Esophagitis in an Immunocompetent 17-Year-Old
title_full_unstemmed HSV Esophagitis in an Immunocompetent 17-Year-Old
title_sort hsv esophagitis in an immunocompetent 17-year-old
publisher SAGE Publishing
publishDate 2021
url https://doaj.org/article/2cb6d24c869f46b7a6efe55fc083ec5a
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AT victoriarahamanmd hsvesophagitisinanimmunocompetent17yearold
AT xinghoumd hsvesophagitisinanimmunocompetent17yearold
AT russellwsteelemd hsvesophagitisinanimmunocompetent17yearold
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