A xanthene derivative, DS20060511, attenuates glucose intolerance by inducing skeletal muscle-specific GLUT4 translocation in mice
Furuzono et al. identify DS20060511, a skeletal muscle cell-specific GLUT4 translocation enhancer. They find that DS20060511 have remarkable effects on lowering blood glucose and enhancing skeletal muscle glucose uptake via GLUT4, highlighting its potential as antidiabetic medicine.
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Nature Portfolio
2021
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oai:doaj.org-article:2cbb8b9c1de048938471e2d57c2bf08b2021-12-02T16:46:33ZA xanthene derivative, DS20060511, attenuates glucose intolerance by inducing skeletal muscle-specific GLUT4 translocation in mice10.1038/s42003-021-02491-62399-3642https://doaj.org/article/2cbb8b9c1de048938471e2d57c2bf08b2021-08-01T00:00:00Zhttps://doi.org/10.1038/s42003-021-02491-6https://doaj.org/toc/2399-3642Furuzono et al. identify DS20060511, a skeletal muscle cell-specific GLUT4 translocation enhancer. They find that DS20060511 have remarkable effects on lowering blood glucose and enhancing skeletal muscle glucose uptake via GLUT4, highlighting its potential as antidiabetic medicine.Shinji FuruzonoTetsuya KubotaJunki TauraMasahiro KonishiAsuka NaitoMasato TsutsuiHiroshi KarasawaNaoto KubotaTakashi KadowakiNature PortfolioarticleBiology (General)QH301-705.5ENCommunications Biology, Vol 4, Iss 1, Pp 1-13 (2021) |
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Biology (General) QH301-705.5 |
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Biology (General) QH301-705.5 Shinji Furuzono Tetsuya Kubota Junki Taura Masahiro Konishi Asuka Naito Masato Tsutsui Hiroshi Karasawa Naoto Kubota Takashi Kadowaki A xanthene derivative, DS20060511, attenuates glucose intolerance by inducing skeletal muscle-specific GLUT4 translocation in mice |
description |
Furuzono et al. identify DS20060511, a skeletal muscle cell-specific GLUT4 translocation enhancer. They find that DS20060511 have remarkable effects on lowering blood glucose and enhancing skeletal muscle glucose uptake via GLUT4, highlighting its potential as antidiabetic medicine. |
format |
article |
author |
Shinji Furuzono Tetsuya Kubota Junki Taura Masahiro Konishi Asuka Naito Masato Tsutsui Hiroshi Karasawa Naoto Kubota Takashi Kadowaki |
author_facet |
Shinji Furuzono Tetsuya Kubota Junki Taura Masahiro Konishi Asuka Naito Masato Tsutsui Hiroshi Karasawa Naoto Kubota Takashi Kadowaki |
author_sort |
Shinji Furuzono |
title |
A xanthene derivative, DS20060511, attenuates glucose intolerance by inducing skeletal muscle-specific GLUT4 translocation in mice |
title_short |
A xanthene derivative, DS20060511, attenuates glucose intolerance by inducing skeletal muscle-specific GLUT4 translocation in mice |
title_full |
A xanthene derivative, DS20060511, attenuates glucose intolerance by inducing skeletal muscle-specific GLUT4 translocation in mice |
title_fullStr |
A xanthene derivative, DS20060511, attenuates glucose intolerance by inducing skeletal muscle-specific GLUT4 translocation in mice |
title_full_unstemmed |
A xanthene derivative, DS20060511, attenuates glucose intolerance by inducing skeletal muscle-specific GLUT4 translocation in mice |
title_sort |
xanthene derivative, ds20060511, attenuates glucose intolerance by inducing skeletal muscle-specific glut4 translocation in mice |
publisher |
Nature Portfolio |
publishDate |
2021 |
url |
https://doaj.org/article/2cbb8b9c1de048938471e2d57c2bf08b |
work_keys_str_mv |
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