A xanthene derivative, DS20060511, attenuates glucose intolerance by inducing skeletal muscle-specific GLUT4 translocation in mice

Furuzono et al. identify DS20060511, a skeletal muscle cell-specific GLUT4 translocation enhancer. They find that DS20060511 have remarkable effects on lowering blood glucose and enhancing skeletal muscle glucose uptake via GLUT4, highlighting its potential as antidiabetic medicine.

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Auteurs principaux:	Shinji Furuzono, Tetsuya Kubota, Junki Taura, Masahiro Konishi, Asuka Naito, Masato Tsutsui, Hiroshi Karasawa, Naoto Kubota, Takashi Kadowaki
Format:	article
Langue:	EN
Publié:	Nature Portfolio 2021
Sujets:	Biology (General) QH301-705.5
Accès en ligne:	https://doaj.org/article/2cbb8b9c1de048938471e2d57c2bf08b
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spelling	oai:doaj.org-article:2cbb8b9c1de048938471e2d57c2bf08b2021-12-02T16:46:33ZA xanthene derivative, DS20060511, attenuates glucose intolerance by inducing skeletal muscle-specific GLUT4 translocation in mice10.1038/s42003-021-02491-62399-3642https://doaj.org/article/2cbb8b9c1de048938471e2d57c2bf08b2021-08-01T00:00:00Zhttps://doi.org/10.1038/s42003-021-02491-6https://doaj.org/toc/2399-3642Furuzono et al. identify DS20060511, a skeletal muscle cell-specific GLUT4 translocation enhancer. They find that DS20060511 have remarkable effects on lowering blood glucose and enhancing skeletal muscle glucose uptake via GLUT4, highlighting its potential as antidiabetic medicine.Shinji FuruzonoTetsuya KubotaJunki TauraMasahiro KonishiAsuka NaitoMasato TsutsuiHiroshi KarasawaNaoto KubotaTakashi KadowakiNature PortfolioarticleBiology (General)QH301-705.5ENCommunications Biology, Vol 4, Iss 1, Pp 1-13 (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	Biology (General) QH301-705.5
spellingShingle	Biology (General) QH301-705.5 Shinji Furuzono Tetsuya Kubota Junki Taura Masahiro Konishi Asuka Naito Masato Tsutsui Hiroshi Karasawa Naoto Kubota Takashi Kadowaki A xanthene derivative, DS20060511, attenuates glucose intolerance by inducing skeletal muscle-specific GLUT4 translocation in mice
description	Furuzono et al. identify DS20060511, a skeletal muscle cell-specific GLUT4 translocation enhancer. They find that DS20060511 have remarkable effects on lowering blood glucose and enhancing skeletal muscle glucose uptake via GLUT4, highlighting its potential as antidiabetic medicine.
format	article
author	Shinji Furuzono Tetsuya Kubota Junki Taura Masahiro Konishi Asuka Naito Masato Tsutsui Hiroshi Karasawa Naoto Kubota Takashi Kadowaki
author_facet	Shinji Furuzono Tetsuya Kubota Junki Taura Masahiro Konishi Asuka Naito Masato Tsutsui Hiroshi Karasawa Naoto Kubota Takashi Kadowaki
author_sort	Shinji Furuzono
title	A xanthene derivative, DS20060511, attenuates glucose intolerance by inducing skeletal muscle-specific GLUT4 translocation in mice
title_short	A xanthene derivative, DS20060511, attenuates glucose intolerance by inducing skeletal muscle-specific GLUT4 translocation in mice
title_full	A xanthene derivative, DS20060511, attenuates glucose intolerance by inducing skeletal muscle-specific GLUT4 translocation in mice
title_fullStr	A xanthene derivative, DS20060511, attenuates glucose intolerance by inducing skeletal muscle-specific GLUT4 translocation in mice
title_full_unstemmed	A xanthene derivative, DS20060511, attenuates glucose intolerance by inducing skeletal muscle-specific GLUT4 translocation in mice
title_sort	xanthene derivative, ds20060511, attenuates glucose intolerance by inducing skeletal muscle-specific glut4 translocation in mice
publisher	Nature Portfolio
publishDate	2021
url	https://doaj.org/article/2cbb8b9c1de048938471e2d57c2bf08b
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A xanthene derivative, DS20060511, attenuates glucose intolerance by inducing skeletal muscle-specific GLUT4 translocation in mice

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