Whole-brain 3D mapping of human neural transplant innervation

Transplantation of cells into the central nervous system has developed into a major avenue for replacing neurons lost to neurodegenerative disease. Here the authors develop an approach combining viral-based transynaptic tracing labeling and whole brain imaging to trace synaptic innervation of human...

Descripción completa

Guardado en:

Detalles Bibliográficos
Autores principales:	Jonas Doerr, Martin Karl Schwarz, Dirk Wiedermann, Anke Leinhaas, Alina Jakobs, Florian Schloen, Inna Schwarz, Michael Diedenhofen, Nils Christian Braun, Philipp Koch, Daniel A. Peterson, Ulrich Kubitscheck, Mathias Hoehn, Oliver Brüstle
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2017
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/2cbee1c0f4eb4c74965a509ea89d4813
Etiquetas:	Agregar Etiqueta Sin Etiquetas, Sea el primero en etiquetar este registro!

id	oai:doaj.org-article:2cbee1c0f4eb4c74965a509ea89d4813
record_format	dspace
spelling	oai:doaj.org-article:2cbee1c0f4eb4c74965a509ea89d48132021-12-02T15:38:53ZWhole-brain 3D mapping of human neural transplant innervation10.1038/ncomms141622041-1723https://doaj.org/article/2cbee1c0f4eb4c74965a509ea89d48132017-01-01T00:00:00Zhttps://doi.org/10.1038/ncomms14162https://doaj.org/toc/2041-1723Transplantation of cells into the central nervous system has developed into a major avenue for replacing neurons lost to neurodegenerative disease. Here the authors develop an approach combining viral-based transynaptic tracing labeling and whole brain imaging to trace synaptic innervation of human neurons transplanted into a mouse background.Jonas DoerrMartin Karl SchwarzDirk WiedermannAnke LeinhaasAlina JakobsFlorian SchloenInna SchwarzMichael DiedenhofenNils Christian BraunPhilipp KochDaniel A. PetersonUlrich KubitscheckMathias HoehnOliver BrüstleNature PortfolioarticleScienceQENNature Communications, Vol 8, Iss 1, Pp 1-7 (2017)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Jonas Doerr Martin Karl Schwarz Dirk Wiedermann Anke Leinhaas Alina Jakobs Florian Schloen Inna Schwarz Michael Diedenhofen Nils Christian Braun Philipp Koch Daniel A. Peterson Ulrich Kubitscheck Mathias Hoehn Oliver Brüstle Whole-brain 3D mapping of human neural transplant innervation
description	Transplantation of cells into the central nervous system has developed into a major avenue for replacing neurons lost to neurodegenerative disease. Here the authors develop an approach combining viral-based transynaptic tracing labeling and whole brain imaging to trace synaptic innervation of human neurons transplanted into a mouse background.
format	article
author	Jonas Doerr Martin Karl Schwarz Dirk Wiedermann Anke Leinhaas Alina Jakobs Florian Schloen Inna Schwarz Michael Diedenhofen Nils Christian Braun Philipp Koch Daniel A. Peterson Ulrich Kubitscheck Mathias Hoehn Oliver Brüstle
author_facet	Jonas Doerr Martin Karl Schwarz Dirk Wiedermann Anke Leinhaas Alina Jakobs Florian Schloen Inna Schwarz Michael Diedenhofen Nils Christian Braun Philipp Koch Daniel A. Peterson Ulrich Kubitscheck Mathias Hoehn Oliver Brüstle
author_sort	Jonas Doerr
title	Whole-brain 3D mapping of human neural transplant innervation
title_short	Whole-brain 3D mapping of human neural transplant innervation
title_full	Whole-brain 3D mapping of human neural transplant innervation
title_fullStr	Whole-brain 3D mapping of human neural transplant innervation
title_full_unstemmed	Whole-brain 3D mapping of human neural transplant innervation
title_sort	whole-brain 3d mapping of human neural transplant innervation
publisher	Nature Portfolio
publishDate	2017
url	https://doaj.org/article/2cbee1c0f4eb4c74965a509ea89d4813
work_keys_str_mv	AT jonasdoerr wholebrain3dmappingofhumanneuraltransplantinnervation AT martinkarlschwarz wholebrain3dmappingofhumanneuraltransplantinnervation AT dirkwiedermann wholebrain3dmappingofhumanneuraltransplantinnervation AT ankeleinhaas wholebrain3dmappingofhumanneuraltransplantinnervation AT alinajakobs wholebrain3dmappingofhumanneuraltransplantinnervation AT florianschloen wholebrain3dmappingofhumanneuraltransplantinnervation AT innaschwarz wholebrain3dmappingofhumanneuraltransplantinnervation AT michaeldiedenhofen wholebrain3dmappingofhumanneuraltransplantinnervation AT nilschristianbraun wholebrain3dmappingofhumanneuraltransplantinnervation AT philippkoch wholebrain3dmappingofhumanneuraltransplantinnervation AT danielapeterson wholebrain3dmappingofhumanneuraltransplantinnervation AT ulrichkubitscheck wholebrain3dmappingofhumanneuraltransplantinnervation AT mathiashoehn wholebrain3dmappingofhumanneuraltransplantinnervation AT oliverbrustle wholebrain3dmappingofhumanneuraltransplantinnervation
_version_	1718386040208621568

Whole-brain 3D mapping of human neural transplant innervation

Ejemplares similares