Specific marking of hESCs-derived hematopoietic lineage by WAS-promoter driven lentiviral vectors.

Specific marking of hESCs-derived hematopoietic lineage by WAS-promoter driven lentiviral vectors.

Genetic manipulation of human embryonic stem cells (hESCs) is instrumental for tracing lineage commitment and to studying human development. Here we used hematopoietic-specific Wiskott-Aldrich syndrome gene (WAS)-promoter driven lentiviral vectors (LVs) to achieve highly specific gene expression in...

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Bibliographic Details
Main Authors: Pilar Muñoz, Miguel G Toscano, Pedro J Real, Karim Benabdellah, Marién Cobo, Clara Bueno, Verónica Ramos-Mejía, Pablo Menendez, Per Anderson, Francisco Martín
Format: article
Language:EN
Published: Public Library of Science (PLoS) 2012
Subjects:
Medicine
R
Science
Q
Online Access:https://doaj.org/article/2cc09e86081a40df98800d1d0a3ee8b4
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