Cell fate in antiviral response arises in the crosstalk of IRF, NF-κB and JAK/STAT pathways

Cell fate in antiviral response arises in the crosstalk of IRF, NF-κB and JAK/STAT pathways

Innate immunity combines intra- and intercellular signalling to develop responses that limit pathogen spread. Here the authors analyse feedback and feedforward loops connecting IRF3, NF-κB and STAT pathways, and suggest they allow coordinating cell fate decisions in cellular populations in response...

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Autores principales: Maciej Czerkies, Zbigniew Korwek, Wiktor Prus, Marek Kochańczyk, Joanna Jaruszewicz-Błońska, Karolina Tudelska, Sławomir Błoński, Marek Kimmel, Allan R. Brasier, Tomasz Lipniacki
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2018
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Science
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Acceso en línea:https://doaj.org/article/2cd07c1b1ec6412cbcb7351e15f8b2da
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